Human and animal studies have revealed a strong association between periconceptional
environmental factors, such as poor maternal diet, and an increased propensity for …

Although the association between maternal periconceptional diet and adult offspring health
is well characterised, our understanding of the impact of paternal nutrition at the time of …

BACKGROUND AND AIMS: Low birth weight affects 1 in every 7 babies born globally and
can predict a lifetime of increased risk for adverse health outcomes, including cardiovascular …

Periconceptional environment may influence embryo development, ultimately affecting adult
health. Here, we review the rodent model of maternal low-protein diet specifically during the …

Epidemiological findings indicate that transient environmental influences during perinatal
life, especially nutrition, may have deleterious heritable health effects lasting for the entire …

Previously, we have shown that a maternal low protein diet, fed exclusively during the
preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the …

Poor maternal nutrition during pregnancy can alter postnatal phenotype and increase
susceptibility to adult cardiovascular and metabolic diseases. However, underlying …

Environmental perturbations during early mammalian development can affect aspects of
offspring growth and cardiovascular health. We have demonstrated previously that maternal …

Defining the mechanisms underlying the programming of early life growth is fundamental for
improving adult health and wellbeing. While the association between maternal diet, offspring …

Epidemiological studies have indicated that susceptibility of human adults to hypertension
and cardiovascular disease may result from intrauterine growth restriction and low birth …