[HTML][HTML] Aquaporin 5 facilitates corneal epithelial wound healing and nerve regeneration by reactivating Akt signaling pathway
Y Liu, G Di, Y Wang, D Chong, X Cao… - The American journal of …, 2021 - Elsevier
Aquaporins (AQPs) are a highly conserved group of membrane proteins that play critical
roles in water and small solute transport across epithelial and endothelial barriers. The aim …
roles in water and small solute transport across epithelial and endothelial barriers. The aim …
Aquaporin 5 promotes corneal wound healing
SS Kumari, M Varadaraj, AG Menon… - Experimental eye …, 2018 - Elsevier
Aquaporins (AQPs), ordinarily regarded as water channels, have recently been shown to
participate in other cellular functions such as cell-to-cell adhesion, cell migration, cell …
participate in other cellular functions such as cell-to-cell adhesion, cell migration, cell …
[HTML][HTML] Effect of down-regulation of aquaporins in human corneal endothelial and epithelial cell lines
J Shankardas, RV Patil, JK Vishwanatha - Molecular Vision, 2010 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to determine the effects of down-regulation of
Aquaporin 1 (AQP1) and Aquaporin 5 (AQP5) on cell proliferation and migration in human …
Aquaporin 1 (AQP1) and Aquaporin 5 (AQP5) on cell proliferation and migration in human …
Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models
J Ruiz-Ederra, AS Verkman - Experimental eye research, 2009 - Elsevier
Aquaporin-1 (AQP1) water channels are expressed in corneal keratocytes, which become
activated and migrate following corneal wounding. The purpose of this study was to …
activated and migrate following corneal wounding. The purpose of this study was to …
Loss of aquaporin 5 contributes to the corneal epithelial pathogenesis via Wnt/β‐catenin pathway
Y Wang, G Di, K Zhang, Y Bai, X Cao… - The FASEB …, 2023 - Wiley Online Library
AQP5 plays a crucial role in maintaining corneal transparency and the barrier function of the
cornea. Here, we found that in the corneas of Aqp5−/− mice at older than 6 months, loss of …
cornea. Here, we found that in the corneas of Aqp5−/− mice at older than 6 months, loss of …
Role of aquaporins in corneal healing post chemical injury
Aquaporins (AQPs) are transmembrane water channel proteins that regulate the movement
of water through the plasma membrane in various tissues including cornea. The cornea is …
of water through the plasma membrane in various tissues including cornea. The cornea is …
[HTML][HTML] Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization
MH Levin, AS Verkman - Investigative ophthalmology & visual …, 2006 - tvst.arvojournals.org
purpose. To determine a role for the water-and glycerol-transporting protein aquaporin-3
(AQP3) in mammalian corneal epithelium, where it is expressed but has no known function …
(AQP3) in mammalian corneal epithelium, where it is expressed but has no known function …
Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing
M Hara-Chikuma, AS Verkman - Journal of Molecular Medicine, 2008 - Springer
Healing of skin wounds is a multi-step process involving the migration and proliferation of
basal keratinocytes in epidermis, which strongly express the water/glycerol-transporting …
basal keratinocytes in epidermis, which strongly express the water/glycerol-transporting …
Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling
JR Thiagarajah, AS Verkman - Journal of Biological Chemistry, 2002 - ASBMB
Two aquaporin (AQP)-type water channels are expressed in mammalian cornea, AQP1 in
endothelial cells and AQP5 in epithelial cells. To test whether these aquaporins are involved …
endothelial cells and AQP5 in epithelial cells. To test whether these aquaporins are involved …
[HTML][HTML] Spatial expression of aquaporin 5 in mammalian cornea and lens, and regulation of its localization by phosphokinase A
SS Kumari, M Varadaraj, VS Yerramilli… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose Aquaporins (AQPs) play a significant role in the movement of water across the
plasma membrane. In the eye, the cornea and lens are avascular with unique …
plasma membrane. In the eye, the cornea and lens are avascular with unique …