A clinical trial of frozen platelets: rationale, protocol and pilot analysis plan
Introduction Platelets have a short shelf life and may be discarded due to expiry. Smaller
Australian hospitals often cannot justify keeping platelet units on‐site. Cryopreserved …
Australian hospitals often cannot justify keeping platelet units on‐site. Cryopreserved …
CLIP (cryopreserved vs. liquid platelets for surgical bleeding): Protocol for a randomised controlled trial
Methods: CLIP is a 90-patient, 4-hospital pilot blinded randomised controlled effectiveness
trial of cryopreserved platelets in comparison to apheresis platelets. Outcomes that will be …
trial of cryopreserved platelets in comparison to apheresis platelets. Outcomes that will be …
Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non …
MC Reade, DC Marks, B Howe, S McGuinness… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Cryopreservation at− 80° C in dimethylsulphoxide extends platelet shelf-life
from 7 days to 2 years. Only limited comparative trial data supports the safety and …
from 7 days to 2 years. Only limited comparative trial data supports the safety and …
[HTML][HTML] Protocol: Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised …
MC Reade, DC Marks, B Howe, S McGuinness… - BMJ Open, 2022 - ncbi.nlm.nih.gov
Introduction Cryopreservation at− 80 C in dimethylsulphoxide extends platelet shelf-life from
7 days to 2 years. Only limited comparative trial data supports the safety and effectiveness of …
7 days to 2 years. Only limited comparative trial data supports the safety and effectiveness of …
A pilot randomized clinical trial of cryopreserved versus liquid‐stored platelet transfusion for bleeding in cardiac surgery: the cryopreserved versus liquid platelet‐New …
S McGuinness, R Charlewood, E Gilder… - Vox …, 2022 - Wiley Online Library
Abstract Background and Objectives Platelets for transfusion have a shelf‐life of 7 days,
limiting availability and leading to wastage. Cryopreservation at− 80° C extends shelf‐life to …
limiting availability and leading to wastage. Cryopreservation at− 80° C extends shelf‐life to …
A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP‐I trial (Editorial, p. 2759)
BACKGROUND Cryopreservation extends platelet (PLT) shelf life from 5 to 7 days to 2 to 4
years. However, only 73 patients have been transfused cryopreserved PLTs in published …
years. However, only 73 patients have been transfused cryopreserved PLTs in published …
[PDF][PDF] Vox Sanguinis International Forum on platelet cryopreservation: Summary.
CS Cohn, LJ Dumont, M Lozano, DC Marks… - Vox …, 2017 - academia.edu
The demand for platelets continues to rise, outstripping supply worldwide. In higher-income
countries, cancer patients remain platelet transfusion dependent for extended periods …
countries, cancer patients remain platelet transfusion dependent for extended periods …
Frozen platelets for rural Australia: the CLIP trial
Commenting on our review of frozen blood products1 in the previous issue of Anaesthesia
and Intensive Care, Dr Rowe from Armidale in country NSW eloquently highlights the clinical …
and Intensive Care, Dr Rowe from Armidale in country NSW eloquently highlights the clinical …
[HTML][HTML] Design of the randomized controlled trial comparing dimethyl sulfoxide cryopreserved platelets to liquid stored platelets in patients undergoing …
G Whitman, R Kramer, K Tanaka, J Holcomb… - JTCVS open, 2023 - Elsevier
Objective Dimethylsulfoxide-cryopreserved platelets are being evaluated for treatment of
acute hemorrhage in patients with thrombocytopenia or platelet dysfunction when liquid …
acute hemorrhage in patients with thrombocytopenia or platelet dysfunction when liquid …
The use of frozen platelets for the treatment of bleeding
DJB Kleinveld, NP Juffermans, F Noorman - Annual Update in Intensive …, 2020 - Springer
Frozen platelets have been used for the treatment of bleeding patients in military and
austere settings. In addition to the advantage of a prolonged shelf life, following thawing …
austere settings. In addition to the advantage of a prolonged shelf life, following thawing …