Objective: The authors investigated the pathways (genetic, environmental, lifestyle, medical)
leading to inflammation in major depressive disorder using C-reactive protein (CRP) …

BackgroundAlthough there is cross-sectional evidence that changes in the immune system
contribute to the pathophysiology of depression, longitudinal data capable of elucidating …

Background Elevated levels of plasma C-reactive protein (CRP) have been associated with
many diseases including depression, but it remains unclear whether this association is …

Context The pathogenesis of depression is not fully understood, but studies suggest that low-
grade systemic inflammation contributes to the development of depression. Objective To test …

Little is known about the association of depression subtypes with inflammatory markers
predictive of coronary artery disease. In a sample of younger adults representative of the US …

Objective: To test whether depression is independently associated with elevated levels of C-
reactive protein (CRP) in a large nationwide population-based sample. Methods …

Background Depression has been associated with chronic changes in the serum
concentration of C-reactive protein (CRP) in observational studies, but it is unclear if this …

Introduction Population-based studies have associated inflammation, particularly higher C-
reactive protein (CRP), with depressive severity, but clinical trials in major depressive …

Objective: Evidence from anti-inflammatory drug trials for the treatment of depression has
been inconsistent. This may be ascribed to the differing symptom-specific effects of …

BACKGROUND: Depression is associated with elevated levels of the inflammation marker C-
reactive protein (CRP); yet, the direction of this association remains unclear. This study …