Background Through amplifying inflammatory cascades, IL-17A produced by γδ T cells
potently attracts neutrophils to the site of injury for exacerbating ischemic tissue damage …

Inflammation is a critical factor for development of hypoxic–ischemic (HI) brain injury.
Interleukin-18 (IL-18) is a proinflammatory cytokine expressed in microglia and processed …

Summary Interleukin‐17 (IL‐17) is a cytokine family that includes 6 members, IL‐17A
through IL‐17F, most of them are reported to have pro‐inflammatory role. Through binding to …

Background and Purpose—Stroke causes brain injury with activation of an inflammatory
response that can contribute to injury. We tested the hypothesis that the anti-inflammatory …

Stroke induces a profound neuroinflammatory reaction that leads to secondary cerebral
tissue injury. Interleukin-10 (IL-10) is a key anti-inflammatory cytokine that is endogenously …

Post-stroke inflammation may contribute to secondary brain injury and systemic
immunosuppression. Interleukin (IL)-37 is an immunosuppressive cytokine belonging to the …

Stroke triggers a complex inflammatory process in which the balance between pro-and
antiinflammatory mediators is critical for the development of the brain infarct. However …

Background and Purpose: Emerging evidence highlights the importance of IL33 (interleukin
33) and its receptor (ST2 [interleukin 1 receptor-like 1]) in normal brains and neurological …

Background and Purpose—Interleukin-6 (IL-6) appears to be involved in the inflammatory
response associated with central nervous system (CNS) ischemia. Although IL-6 levels …

Abstract Interleukin-33 (IL-33), a novel member of the IL-1 family, expressed in many tissue
and cell types, is involved in inflammation and immune functions. Previous studies suggest …