Origins of transfer establish networks of functional dependencies for plasmid transfer by conjugation
Plasmids can be transferred between cells by conjugation, thereby driving bacterial
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …
Diverse mobilization strategies facilitate transfer of non-conjugative mobile genetic elements
Highlights•Non-conjugative mobile genetic elements are often mobilized by conjugative
elements.•Element carriage of a relaxase gene is not a strict requirement for mobilization.•A …
elements.•Element carriage of a relaxase gene is not a strict requirement for mobilization.•A …
Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids
C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …
the plasmids encode the functions necessary to conjugate autonomously, the others being …
Vertical and horizontal gene transfer tradeoffs direct plasmid fitness
JH Bethke, HR Ma, R Tsoi, L Cheng… - Molecular Systems …, 2023 - embopress.org
Plasmid fitness is directed by two orthogonal processes—vertical transfer through cell
division and horizontal transfer through conjugation. When considered individually …
division and horizontal transfer through conjugation. When considered individually …
Mobility of plasmids
C Smillie, MP Garcillán-Barcia… - Microbiology and …, 2010 - Am Soc Microbiol
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …
They code for genes involved in many aspects of microbial biology, including detoxication …
[HTML][HTML] Mating pair stabilization mediates bacterial conjugation species specificity
WW Low, JLC Wong, LC Beltran, C Seddon… - Nature …, 2022 - nature.com
Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
Beyond horizontal gene transfer: the role of plasmids in bacterial evolution
J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
accessory genes by horizontal gene transfer. However, recent studies have revealed that …
[HTML][HTML] Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation
Conjugation is one mechanism for intra-and inter-species horizontal gene transfer among
bacteria. Conjugative elements have been instrumental in many bacterial species to face the …
bacteria. Conjugative elements have been instrumental in many bacterial species to face the …
Plasmids spread very fast in heterogeneous bacterial communities
Conjugative plasmids can mediate gene transfer between bacterial taxa in diverse
environments. The ability to donate the F-type conjugative plasmid R1 greatly varies among …
environments. The ability to donate the F-type conjugative plasmid R1 greatly varies among …
Plasmids pick a bacterial partner before committing to conjugation
Bacterial conjugation was first described by Lederberg and Tatum in the 1940s following the
discovery of the F plasmid. During conjugation a plasmid is transferred unidirectionally from …
discovery of the F plasmid. During conjugation a plasmid is transferred unidirectionally from …