Origins of transfer establish networks of functional dependencies for plasmid transfer by conjugation

M Ares-Arroyo, C Coluzzi, EPC Rocha - Nucleic acids research, 2023 - academic.oup.com
Plasmids can be transferred between cells by conjugation, thereby driving bacterial
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …

Diverse mobilization strategies facilitate transfer of non-conjugative mobile genetic elements

JP Ramsay, N Firth - Current opinion in microbiology, 2017 - Elsevier
Highlights•Non-conjugative mobile genetic elements are often mobilized by conjugative
elements.•Element carriage of a relaxase gene is not a strict requirement for mobilization.•A …

Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids

C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

Vertical and horizontal gene transfer tradeoffs direct plasmid fitness

JH Bethke, HR Ma, R Tsoi, L Cheng… - Molecular Systems …, 2023 - embopress.org
Plasmid fitness is directed by two orthogonal processes—vertical transfer through cell
division and horizontal transfer through conjugation. When considered individually …

Mobility of plasmids

C Smillie, MP Garcillán-Barcia… - Microbiology and …, 2010 - Am Soc Microbiol
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …

[HTML][HTML] Mating pair stabilization mediates bacterial conjugation species specificity

WW Low, JLC Wong, LC Beltran, C Seddon… - Nature …, 2022 - nature.com
Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

[HTML][HTML] Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation

Z Baharoglu, D Bikard, D Mazel - PLoS genetics, 2010 - journals.plos.org
Conjugation is one mechanism for intra-and inter-species horizontal gene transfer among
bacteria. Conjugative elements have been instrumental in many bacterial species to face the …

Plasmids spread very fast in heterogeneous bacterial communities

F Dionisio, I Matic, M Radman, OR Rodrigues… - Genetics, 2002 - academic.oup.com
Conjugative plasmids can mediate gene transfer between bacterial taxa in diverse
environments. The ability to donate the F-type conjugative plasmid R1 greatly varies among …

Plasmids pick a bacterial partner before committing to conjugation

G Frankel, S David, WW Low, C Seddon… - Nucleic Acids …, 2023 - academic.oup.com
Bacterial conjugation was first described by Lederberg and Tatum in the 1940s following the
discovery of the F plasmid. During conjugation a plasmid is transferred unidirectionally from …