There is a close anatomical and functional relationship between adipose tissue and blood
vessels. The crosstalk between these two organs is vital to both metabolic and vascular …

The prevalence of obesity is rising dramatically in developed and developing countries.
Obesity contributes to increased mortality from numerous causes, but the most important of …

Obesity is associated with the development of vascular insulin resistance; however,
pathophysiological mechanisms are poorly understood. We sought to investigate the role of …

Much of the focus of research in angiogenesis has been on the molecular mechanisms
regulating various critical endothelial cell processes such as migration, proliferation and …

Over the past 2 to 3 decades, research has focused on the changes in the vascular effects of
insulin occurring in insulin resistant states like obesity. Consistent evidence indicates that …

Obesity and obesity-associated clinical disorders are becoming an increasing public health
burden. In this perspective, we postulate that impairment of microvascular function links …

Background The expansion of adipose tissue is linked to the development of its vasculature,
which appears to have the potential to regulate the onset of obesity. However, at present …

Human obesity is associated with insulin resistance and often results in a number of
metabolic abnormalities and cardiovascular complications. Over the past decades …

Obesity is a metabolic disorder of increasing prevalence worldwide and a risk factor for the
development of insulin resistance (IR), metabolic syndrome and type 2 diabetes. Obesity is …