Extracellular matrix (ECM) remodeling has been implicated in the irreversible obstruction of
airways and destruction of alveolar tissue in chronic obstructive pulmonary disease (COPD) …

The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM)
contains the main building blocks of both components. The ECM provides physical support …

Background The role of the extracellular matrix (ECM) structure and remodeling thereof in
lung diseases is gaining importance. Pathology-related changes in ECM turnover may result …

Background Exacerbations of chronic obstructive pulmonary disease (COPD) contribute
significantly to disease progression. However, the effect on tissue structure and turnover is …

The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …

Background Chronic obstructive pulmonary disease (COPD) is characterized by airflow
obstruction and loss of lung tissue mainly consisting of extracellular matrix (ECM). Three of …

Remodeling of airways and blood vessels is an important feature in chronic obstructive
pulmonary disease (COPD). By using immunohistochemical analysis, we examined …

The extracellular matrix (ECM) is not just a three-dimensional scaffold that provides stable
support for all cells in the lungs, but also an important component of chronic fibrotic airway …

The pulmonary extracellular matrix (ECM) is a complex network of proteins which primarily
defines tissue architecture and regulates various biochemical and biophysical processes. It …

Glycosaminoglycans (GAGs) and collagens are extracellular matrix (ECM) molecules that
play a significant role in the structure and function of the lung. We aimed to investigate the …