Translational research has revolutionized how we develop new treatments for cancer
patients. The change from an organ-centric concept guiding treatment choice towards deep …

Personalized cancer therapy is based on the precept that detailed molecular
characterization of the patient's tumour and its microenvironment will enable tailored …

Many experts agree that personalized cancer medicine, defined here as treatment based on
the molecular characteristics of a tumor from an individual patient, has great potential in the …

Background Until recently, patients who have the same type and stage of cancer all receive
the same treatment. It has been established, however, that individuals with the same …

Personalized medicine (PM) or precision medicine in oncology is an emerging approach for
tumor treatment and prevention that takes into account inter-and intra-tumor variability in …

BACKGROUND The practice of personalized medicine has made large strides since the
introduction of high-throughput technologies and the vast improvements in computational …

Targeted therapy is the key for improving overall survival while decreasing the undesirable
adverse effects of cancer treatment. Patients who received matched targeted therapies …

Cancer chemotherapy is in evolution from non-specific cytotoxic drugs that damage both
tumour and normal cells to more specific agents and immunotherapy approaches. Targeted …

This article provides an overview of the research, beginning a century ago, that has led to
the current use of genomically informed methods for selection of targeted therapies to treat …

Cancer is a group of diseases characterized by the uncontrolled growth and spread of
abnormal cells and oncology is a branch of medicine that deals with tumors. The last decade …