[HTML][HTML] Rodent models of amyloid-beta feature of Alzheimer's disease: development and potential treatment implications
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide and
causes severe financial and social burdens. Despite much research on the pathogenesis of …
causes severe financial and social burdens. Despite much research on the pathogenesis of …
[HTML][HTML] Mouse models of Alzheimer's disease
M Yokoyama, H Kobayashi, L Tatsumi… - Frontiers in Molecular …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory loss
and personality changes, eventually leading to dementia. The pathological hallmarks of AD …
and personality changes, eventually leading to dementia. The pathological hallmarks of AD …
Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions
M Kitazawa, R Medeiros… - Current pharmaceutical …, 2012 - ingentaconnect.com
Alzheimer disease (AD) is the leading cause of dementia among elderly. Currently, no
effective treatment is available for AD. Analysis of transgenic mouse models of AD has …
effective treatment is available for AD. Analysis of transgenic mouse models of AD has …
Animal and cellular models of Alzheimer's disease: Progress, promise, and future approaches
L Trujillo-Estrada, E Sanchez-Mejias… - The …, 2022 - journals.sagepub.com
Alzheimer's disease (AD) is an incurable neurodegenerative disease affecting over 45
million people worldwide. Transgenic mouse models have made remarkable contributions …
million people worldwide. Transgenic mouse models have made remarkable contributions …
[HTML][HTML] Animal models of Alzheimer's disease: preclinical insights and challenges
QQ Xu, W Yang, M Zhong, ZX Lin, NE Gray… - Acta Materia …, 2023 - scienceopen.com
Alzheimer's disease (AD), an irreversible neurodegenerative disease that progressively
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …
Past to future: what animal models have taught us about Alzheimer's disease
AC Martini, S Forner, L Trujillo-Estrada… - Journal of …, 2018 - content.iospress.com
Alzheimer's disease (AD) impairs memory and causes significant cognitive deficits. The
disease course is prolonged, with a poor prognosis, and thus exacts an enormous economic …
disease course is prolonged, with a poor prognosis, and thus exacts an enormous economic …
Genetically modified mice models for Alzheimer's disease
S Sankaranarayanan - Current Topics in Medicinal Chemistry, 2006 - ingentaconnect.com
Transgenic mice models for Alzheimer's disease (AD) are essential to the understanding of
disease pathophysiology, develop robust behavioral models and predict outcomes from …
disease pathophysiology, develop robust behavioral models and predict outcomes from …
Selecting a mouse model of Alzheimer's disease
J Chin - … Disease and Frontotemporal Dementia: Methods and …, 2011 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease and cause of
dementia. Significant strides toward understanding and developing therapies for AD have …
dementia. Significant strides toward understanding and developing therapies for AD have …
Recent rodent models for Alzheimer's disease: clinical implications and basic research
Alzheimer's disease (AD) is the most common origin of dementia in the elderly. Although the
cause of AD remains unknown, several factors have been identified that appear to play a …
cause of AD remains unknown, several factors have been identified that appear to play a …
[HTML][HTML] Mammalian Models in Alzheimer's Research: An Update
A form of dementia distinct from healthy cognitive aging, Alzheimer's disease (AD) is a
complex multi-stage disease that currently afflicts over 50 million people worldwide …
complex multi-stage disease that currently afflicts over 50 million people worldwide …