Chronic obstructive pulmonary disease is a complex disease with heterogeneous
presentation, progression, and structural abnormality that is currently graded solely on …

Chronic obstructive pulmonary disease is a syndrome that encompasses a variety of
pathologies and underlying mechanisms. Progress in understanding mechanisms, testing …

Chronic obstructive pulmonary disease (COPD), characterized by progressive airflow
obstruction due to the combined effects of emphysema and small airways disease, is …

Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow
limitation that is caused by a combination of small airway remodeling and emphysema …

Computed tomographic based indices of emphysematous lung destruction may highlight
differences in disease pathogenesis and further enable the classification of subjects with …

Chronic obstructive pulmonary disease (COPD) is described as airflow limitation that is not
fully reversible. Quantitative assessment of structural changes within the lung that are …

Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and
mortality worldwide and results in substantial social and economic burdens. COPD is a …

Chronic obstructive pulmonary disease (COPD) exhibits significant heterogeneity in its
clinical presentation and rate of disease progression among affected individuals, owing at …

The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Volumetric computed-tomography scans allow diagnosis and quantification of the individual
small airway and emphysema phenotypes present in people with chronic obstructive …