Congenital and perinatal infections are transmitted from mother to infant during pregnancy
across the placenta or during delivery. These infections not only cause pregnancy …

Infections take their greatest toll in early life necessitating robust approaches to protect the
very young. Here, we review the rationale, current state, and future research directions for …

Vaccines have been incredibly successful at stemming the morbidity and mortality of
infectious diseases worldwide. However, there are still no effective vaccines for many …

Essentially, all neonates are exposed to infections, antibiotics, or vaccines early in their
lives. This is especially true for those neonates born underweight or premature. In contrast to …

Newborns, especially those born preterm, are at high risk for infection. Preterm birth rates
appear to be increasing in most countries, with∼ 15 million infants born preterm globally …

Vaccination is the mainstay of preventative medicine for many infectious diseases. Pregnant
women, unborn fetuses, and neonates represent three at-risk populations that can be …

Prenatal maternal immunization is an effective tool to protect mothers and infants from poor
health outcomes due to infectious diseases. We provide an overview of the rationale for the …

The prevention of severe infectious diseases in children through immunization is a well-
recognized, beneficial, and cost-effective strategy worldwide. 17 Neonates and young …

Pathogens that infect the fetus and newborn are known collectively by the acronym TORCH:
Toxoplasma gondii, other, rubella virus, cytomegalovirus and herpes simplex virus …

Children in early infancy do not mount effective antibody responses to many vaccines
against commons infectious pathogens, which results in a window of increased susceptibility …