Background Radiation therapy (RT) to the brain may result in cognitive impairment. The
primary objective of the present study was to examine the relationship between RT dose to …

Background: The extent of radiation therapy (RT)-induced changes in cognitive function is
unknown. RT with protons instead of photons spares the healthy brain tissue more and is …

Purpose Radiation-induced cognitive decline is relatively common after treatment for
primary and metastatic brain tumors; however, identifying dosimetric parameters that are …

Objective: The neurocognitive sequelae of therapeutic cranial irradiation are not well
characterized in adults with primary brain tumors. To address this problem, we prospectively …

Background and purpose To prospectively evaluate hippocampal radiation dose volume
effects and memory decline following cranial irradiation. Material and methods Effects of …

The objective of the current study was to evaluate the acute effects of cranial radiation
therapy (CNS-RT) using different radiation doses (0, 1.8, 2, 3,≥ 20 Gy) on cognitive function …

Radiotherapy (RT) is a proven curative and palliative therapeutic tool in the treatment of a
wide variety of primary and metastatic brain tumors in adults. Recent advances in …

Background Hippocampus is considered to be the seat for neurocognitive functions.
Avoidance of hippocampus during radiotherapy to brain may serve to preserve various …

Background Hippocampal avoidance has been suggested as a strategy to reduce short-term
memory decline in adults receiving whole-brain radiation therapy (RT). The purpose of this …

Radiotherapy (RT) has proven to be an effective therapeutic tool in treatment of a wide
variety of brain tumors; however, it has a negative impact on quality of life and …