Atherosclerosis plays a significant role in the development of cardiovascular diseases, the
leading cause of death worldwide. Modification of low-density lipoproteins (LDLs) is a critical …

Atherosclerotic diseases are the leading cause of mortality in industrialized countries.
Correspondingly, studying the pathogenesis of atherosclerosis and developing new …

The purpose of this review is to revisit in detail the arguments supporting or disproving the
hypothesis that oxidized low-density lipoprotein (LDL) plays a key role in atherosclerotic …

Atherosclerosis is widely regarded as a chronic inflammatory disease that develops as a
consequence of entrapment of low-density lipoprotein (LDL) in the arterial intima. Native …

High blood concentration of low-density lipoprotein (LDL) cholesterol is a major risk factor
for early development of atherosclerosis. Massive accumulation of cholesterol in the arterial …

Although it has been known for long time that atherosclerosis is associated with lipid
deposition, only recently it has been accepted that the plasmatic concentration of …

As in the first reviews of this Special Issue [2, 3], the review by Pirillo and co-workers [8]
states that focus should be shifted from HDL-C levels toward HDL functional properties. The …

Pathogenesis of atherosclerosis and the search for novel therapies and diagnostic markers
remain major problems of modern medicine. Currently available therapeutic approaches are …

One of the first manifestations of atherosclerosis is accumulation of extra-and intracellular
cholesterol esters in the arterial intima. Formation of foam cells is considered as a trigger in …

Generally, atherosclerosis first occurs by the way of accumulation of intracellular and
extracellular lipids in the arterial intima. Foam cells, overloaded by lipids, are the essential …