The 3′-ends of both prokaryotic and eukaryotic mRNA are polyadenylated, but the poly (A)
tracts of prokaryotic mRNA are generally shorter, ranging from 15 to 60 adenylate residues …

The presence of polyadenylate sequences at the 3'-end of mRNA was first observed in
eukaryotic cells about 25 years ago (Darnel1 et al., 1971; Edmonds et al., 1971; Lee et al …

Biological polyadenylation, first recognized as an enzymatic activity, remained an orphan
enzyme until poly A sequences were found on the 3′ ends of eukaryotic mRNAs. Their …

As part of our genetic analysis of mRNA decay in Escherichia coli K-12, we examined the
effect of the pcnB gene [encoding poly (A) polymerase I] on message stability. Eliminating …

Polyadenylation at the 3′ terminus has long been considered a specific feature of mRNA
and a few other unstable RNA species. Here we show that stable RNAs in Escherichia coli …

Many bacterial mRNAs, like those of eukaryotes, carry a polyadenylate sequence at their
3'termini, but neither the function of the bacterial poly (A) moieties nor their biosynthesis …

Post-transcriptional addition of poly (A) tails to the 3′ end of RNA is one of the fundamental
events controlling the functionality and fate of RNA in all kingdoms of life. Although an …

The addition of multiple adenosine residues to the 3'end of eukaryotic cell transcripts has a
key role in generating functional mRNA and in regulating the decay of this RNA (for recent …

Although the first poly (A) polymerase (PAP) was discovered in Escherichia coli in 1962, the
study of polyadenylation in bacteria was largely ignored for the next 30 years. However, with …

Polyadenylation of RNA molecules in bacteria and chloroplasts has been implicated as part
of the RNA degradation pathway. The polyadenylation reaction is performed in Escherichia …