Neurorestoration in Parkinson's disease by cell replacement and endogenous regeneration

A Hermann, M Gerlach, J Schwarz… - Expert opinion on …, 2004 - Taylor & Francis
Parkinson's disease (PD) is characterised by a continuous and selective loss of
dopaminergic neurons in the substantia nigra pars compacta with a subsequent reduction of …

The use of stem cells in regenerative medicine for Parkinson's and Huntington's diseases

L Lescaudron, P Naveilhan… - Current medicinal …, 2012 - ingentaconnect.com
Cell transplantation has been proposed as a means of replacing specific cell populations
lost through neurodegenerative processes such as that seen in Parkinson's or Huntington's …

Restorative approaches in Parkinson's Disease: which cell type wins the race?

AK Meyer, M Maisel, A Hermann, K Stirl… - Journal of the neurological …, 2010 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder and is
characterized by a continuous and selective loss of dopaminergic neurons in the midbrain …

Mesenchymal stem cells and neuroregeneration in Parkinson's disease

A Glavaski-Joksimovic, MC Bohn - Experimental neurology, 2013 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by a
progressive and extensive loss of dopaminergic (DA) neurons in the substantia nigra pars …

Concise review: therapeutic strategies for Parkinson disease based on the modulation of adult neurogenesis

M Geraerts, O Krylyshkina, Z Debyser… - Stem cells, 2007 - academic.oup.com
Parkinson disease (PD) is a progressive neurodegenerative disorder affecting millions of
people worldwide. To date, treatment strategies are mainly symptomatic and aimed at …

[HTML][HTML] Neural stem cell secretome and its role in the treatment of neurodegenerative disorders

Q Zhang, J Li, W An, Y Fan, Q Cao - Journal of integrative …, 2020 - imrpress.com
Neurological diseases in the central nervous system are mostly characterized by the failure
of endogenous repair to restore tissue damage and salvage lost function. Currently, studies …

[HTML][HTML] Human trials of stem cell-derived dopamine neurons for Parkinson's disease: dawn of a new era

RA Barker, M Parmar, L Studer, J Takahashi - Cell stem cell, 2017 - cell.com
Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era,
with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived …

[HTML][HTML] Stem cell transplantation for Parkinson's disease: Current challenges and perspectives

X Zeng, H Qin - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Parkinson's disease is the second most common form of neurodegeneration, and it poses a
major threat to the quality of life of older adults. Stem cell transplantation, which has attracted …

[HTML][HTML] Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson's disease

D Fričová, JA Korchak, AC Zubair - NPJ Regenerative medicine, 2020 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars …

[HTML][HTML] Current status of stem cell-derived therapies for Parkinson's disease: from cell assessment and imaging modalities to clinical trials

SE Jang, L Qiu, LL Chan, EK Tan, L Zeng - Frontiers in neuroscience, 2020 - frontiersin.org
Curative therapies or treatments reversing the progression of Parkinson's disease (PD) have
attracted considerable interest in the last few decades. PD is characterized by the gradual …