Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population

D Tanimura, R Shibata, H Izawa, A Hirashiki… - European journal of …, 2011 - nature.com
Adiponectin is an adipocyte-derived protein that is down-regulated in obesity-linked
disorders. Variants of the adiponectin gene (ADIPOQ) have been shown to affect …

Genomic structure and mutations in adipose-specific gene, adiponectin

M Takahashi, Y Arita, K Yamagata… - International journal of …, 2000 - nature.com
BACKGROUND: Adiponectin is a collagen-like plasma protein specifically synthesized in
adipose tissue. Plasma adiponectin concentrations are decreased in obesity whereas it is …

Adiponectin gene single-nucleotide polymorphisms and treatment response to obesity

K Tsuzaki, K Kotani, N Nagai, K Saiga, Y Sano… - Journal of …, 2009 - Springer
Background: In the adiponectin gene polymorphisms, single-nucleotide polymorphism
(SNP)− 45 and SNP276 have reportedly been associated with obesity, Type 2 diabetes, and …

Multimers and adiponectin gene 276G> T polymorphism in the Japanese population residing in rural areas

K Ishibashi, N Takamura, K Aoyagi, H Yamasaki… - 2007 - degruyter.com
Background: Although it has been shown that high-molecular weight adiponectin is an
active form, few studies have attempted to clarify the relationship between high molecular …

Allele-specific differential expression of a common adiponectin gene polymorphism related to obesity

WS Yang, PL Tsou, WJ Lee, DL Tseng… - Journal of molecular …, 2003 - Springer
Adiponectin gene polymorphisms have recently been reported to be associated with obesity,
insulin sensitivity, and the risk of type 2 diabetes. We examined a T94G polymorphism of the …

The influence of the adiponectin gene on adiponectin concentrations and parameters of metabolic syndrome in non-diabetic Korean women

Y Jang, JS Chae, SJ Koh, YJ Hyun, JY Kim… - Clinica Chimica …, 2008 - Elsevier
BACKGROUND: Concentrations of adiponectin, the protein product of the adipoctye C1q
and collagen-domain-containing (ADIPOQ) gene are associated with type 2 diabetes and …

Common polymorphisms (single-nucleotide polymorphisms SNP+ 45 and SNP+ 276) of the adiponectin gene regulate serum adiponectin concentrations and blood …

F Mousavinasab, T Tähtinen, J Jokelainen… - Molecular genetics and …, 2006 - Elsevier
Epidemiologic studies have shown that serum level of adiponectin, a circulating protein
secreted by adipocytes, predicts the risk of type 2 diabetes and cardiovascular events. Two …

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians …

C Menzaghi, L Salvemini, G Paroni… - Journal of Internal …, 2010 - Wiley Online Library
Menzaghi C, Salvemini L, Paroni G, De Bonis C, Mangiacotti D, Fini G, Doria A, Di Paola R,
Trischitta V (IRCCS “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), Italy …

Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population

PEH Schwarz, S Govindarajalu… - Hormone and …, 2006 - thieme-connect.com
Adiponectin, which is encoded by the ADIPOQ gene, has been shown to modulate insulin
sensitivity and glucose homeostasis. Plasma adiponectin levels are decreased in type 2 …

Adiponectin Isoform Patterns in Ethnic‐Specific ADIPOQ Mutation Carriers: The IRAS Family Study

KL Tabb, C Gao, PJ Hicks, GA Hawkins, JI Rotter… - …, 2017 - Wiley Online Library
Objective Adiponectin is found in human serum in three groups of multimers (high molecular
weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]). Two …