Metastatic melanoma is a fatal malignancy with a high mortality and morbidity. Since the
early 1970s, available medical therapies were limited in improving survival. Surgery …

After primary tumor treatment, 30% of patients with malignant melanoma develop metastatic
disease, usually associated with a poor prognosis. Effective chemotherapeutic regimens for …

Melanoma is the most deadly of skin cancers, and metastatic disease most commonly first
appears in the lungs. Because most patients with early metastatic pulmonary disease are …

Simple Summary Since the introduction of effective systemic therapies (ESTs)(in the form of
both targeted and immuno-based therapies) in the treatment of malignant melanoma, the …

Introduction The lung represents a frequent site of spread for metastatic melanoma, which
has historically been managed with surgical resection achieving promising outcomes. We …

Spread of melanoma can be cutaneous, to distant lymph nodes or to visceral organs such as
the lung (18-36%), liver (14-20%), brain (12-20%) and bone (11-17%)(1). Overall, the lung is …

OBJECTIVES: Although refractory to chemotherapy, metastatic melanoma may respond to
adoptive immunotherapy. As novel treatments evolve, surgeons may be asked to perform …

Background. Surgical therapy plays an important role in the management of selected
patients with metastatic melanoma. Purpose. A retrospective review of 13 patients who …

OBJECTIVES Pulmonary metastasectomy for malignant melanoma requires an
individualized therapeutic decision. Due to recently developed novel treatment options, the …

More than 80% of patients with metastatic melanoma initially show only one distant organ
site involvement, most commonly the lungs. Several studies on patients with pulmonary …