The physiological background of the unusually high cadmium tolerance (MIC50> 2 mM) of
Aspergillus fumigatus Af293 was investigated. The cadmium tolerance of the tested …

Most of the metal transporters in Aspergillus fumigatus are yet uncharacterized. Their role in
fungal metabolism and virulence remains unclear. This paper describes the novel PIB-type …

Abstract The P‐type ATPase CrpA is an important Cu2+/Cd2+ pump in the Aspergilli,
significantly contributing to the heavy metal stress tolerance of these ascomycetous fungi. As …

The transition metals iron and copper are required by virtually all organisms but are toxic in
excess. Acquisition of both metals, as well as resistance to copper excess have previously …

Highlights•Aspergillus fumigatus requires metal ion uptake in the host environment.•Metal-
homeostatic circuits are complex and multifactorial.•Imbalances in metal homeostasis affect …

ABSTRACT Several P1B-type ATPases are important Cd2+/Cu2+ pumps in Aspergillus
species, and they are tightly associated with the heavy metal stress tolerance of these …

Iron: an essential nutrient for Aspergillus fumigatus and a... : Current Opinion in Infectious
Diseases Iron: an essential nutrient for Aspergillus fumigatus and a fulcrum for …

Copper is an essential metal ion that performs many physiological functions in living
organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A …

Aspergillus fumigatus is the most common cause of invasive aspergillosis, a life-threatening
infection mainly affecting immunocompromised patients. The essential metals copper and …

Cadmium is an exceptionally toxic industrial and environmental pollutant classified as a
human carcinogen. In order to provide insight into how we can keep our environment safe …