The interplay between zinc and iron homeostasis in Aspergillus fumigatus under zinc‐replete conditions relies on the iron‐mediated regulation of alternative transcription units of …
R Vicentefranqueira, F Leal, L Marín… - Environmental …, 2019 - Wiley Online Library
Aspergillus fumigatus is a saprophyte fungus that typically grows on organic decaying matter
but can also parasitize immunosuppressed hosts. This is explained, in part, by its great …
but can also parasitize immunosuppressed hosts. This is explained, in part, by its great …
Aspergillus fumigatus survival in alkaline and extreme zinc-limiting environments relies on the induction of a zinc homeostasis system encoded by the zrfC and aspf2 …
Aspergillus fumigatus has three zinc transporter-encoding genes whose expression is
regulated by both pH and the environmental concentration of zinc. We have previously …
regulated by both pH and the environmental concentration of zinc. We have previously …
Cadmium uptake and subcellular compartmentation in the ectomycorrhizal fungus Paxillus involutus
Cadmium uptake and subcellular compartmentation in the ectomycorrhizal fungus Paxillus
involutus were investigated using radiotracer flux analyses. Concentration-dependent Cd2+ …
involutus were investigated using radiotracer flux analyses. Concentration-dependent Cd2+ …
[HTML][HTML] The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages
M Schrettl, O Ibrahim-Granet, S Droin, M Huerre… - Microbes and …, 2010 - Elsevier
Iron plays a central role in manifestation of infections for a variety of pathogens. To ensure
an adequate supply with iron, Aspergillus fumigatus employs extra-and intracellular …
an adequate supply with iron, Aspergillus fumigatus employs extra-and intracellular …
Iron and copper as virulence modulators in human fungal pathogens
Fungal pathogens have evolved sophisticated machinery to precisely balance the fine line
between acquiring essential metals and defending against metal toxicity. Iron and copper …
between acquiring essential metals and defending against metal toxicity. Iron and copper …
Identification of key proteins and pathways in cadmium tolerance of Lactobacillus plantarum strains by proteomic analysis
Our previous study confirmed the protective potential of Lactobacillus plantarum (L.
plantarum) strains in alleviation of cadmium (Cd) toxicity in vivo and demonstrated that the …
plantarum) strains in alleviation of cadmium (Cd) toxicity in vivo and demonstrated that the …
The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus
R Vicentefranqueira, J Amich, L Marín, CI Sánchez… - Genes, 2018 - mdpi.com
One of the most important features that enables Aspergillus fumigatus to grow within a
susceptible individual and to cause disease is its ability to obtain Zn2+ ions from the …
susceptible individual and to cause disease is its ability to obtain Zn2+ ions from the …
[HTML][HTML] Copper homeostasis in Aspergillus fumigatus: opportunities for therapeutic development
J Song, R Li, J Jiang - Frontiers in microbiology, 2019 - frontiersin.org
Aspergillus fumigatus can cause severe invasive aspergillosis in immunocompromised
individuals. Copper, an essential but potentially toxic trace element for A. fumigatus, plays a …
individuals. Copper, an essential but potentially toxic trace element for A. fumigatus, plays a …
Transcriptional response of Aspergillus fumigatus to copper and the role of the Cu chaperones
D Anabosi, Z Meir, Y Shadkchan, M Handelman… - Virulence, 2021 - Taylor & Francis
Aspergillus fumigatus is the leading cause of life-threatening invasive mold infections in
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
A Putative Mitochondrial Iron Transporter MrsA in Aspergillus fumigatus Plays Important Roles in Azole-, Oxidative Stress Responses and Virulence
N Long, X Xu, H Qian, S Zhang, L Lu - Frontiers in microbiology, 2016 - frontiersin.org
Iron is an essential nutrient and enzyme co-factor required for a wide range of cellular
processes, especially for the function of mitochondria. For the opportunistic fungal pathogen …
processes, especially for the function of mitochondria. For the opportunistic fungal pathogen …