Functional characterization of the Aspergillus fumigatus calcineurin

ME da Silva Ferreira, T Heinekamp, A Härtl… - Fungal Genetics and …, 2007 - Elsevier
Aspergillus fumigatus is an aggressive opportunistic pathogen of humans as well as a major
allergen. Environmental sensing and retrieving essential nutrients from the environment are …

Cadmium Accumulation and Tolerance in Bradyrhizobium spp. (Peanut Microsymbionts)

E Bianucci, A Fabra, S Castro - Current microbiology, 2011 - Springer
In this study, the effect of cadmium (Cd) on cell viability and its accumulation in
Bradyrhizobium spp.(peanut microsymbionts) as well as the role of glutathione (GSH) in the …

Virus Infection of Aspergillus fumigatus Compromises the Fungus in Intermicrobial Competition

H Nazik, I Kotta-Loizou, G Sass, RHA Coutts… - Viruses, 2021 - mdpi.com
Aspergillus and Pseudomonas compete in nature, and are the commonest bacterial and
fungal pathogens in some clinical settings, such as the cystic fibrosis lung. Virus infections of …

A contrast of Pb (II), Cd (II), and Cu (II) toxicities to Aspergillus niger through biochemical, morphological, and genetic investigations

L Zhang, X Yang, S Li, L Tang, T Chen, T Gu… - Journal of Hazardous …, 2023 - Elsevier
The toxicity of metals to microorganisms is highly correlated with the type of metal used.
However, the differences in the resistance mechanisms of filamentous fungi to multiple …

Aspergillus fumigatus SidJ mediates intracellular siderophore hydrolysis

M Gründlinger, F Gsaller, M Schrettl… - Applied and …, 2013 - Am Soc Microbiol
Siderophore-mediated iron handling is crucial for the virulence of Aspergillus fumigatus.
Here we identified a new component of its siderophore metabolism, termed SidJ, which is …

Identification of high-affinity copper transporters in Aspergillus fumigatus

YS Park, H Lian, M Chang, CM Kang… - Fungal Genetics and …, 2014 - Elsevier
We investigated the copper metabolism of Aspergillus fumigatus, which has not been
characterized well. We cloned the putative copper transporters ctrA 2 and ctrC from A …

The cytochrome b5 CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus

M Misslinger, F Gsaller, P Hortschansky, C Müller… - Metallomics, 2017 - academic.oup.com
Abstract Cytochrome P450 enzymes (P450) play essential roles in redox metabolism in all
domains of life including detoxification reactions and sterol biosynthesis. The activity of …

Conservation and Loss of a Putative Iron Utilization Gene Cluster among Genotypes of Aspergillus flavus

BN Adhikari, KA Callicott, PJ Cotty - Microorganisms, 2021 - mdpi.com
Iron is an essential component for growth and development. Despite relative abundance in
the environment, bioavailability of iron is limited due to oxidation by atmospheric oxygen into …

Effects of iron chelators on the formation and development of Aspergillus fumigatus biofilm

H Nazik, JC Penner, JA Ferreira… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Iron acquisition is crucial for the growth of Aspergillus fumigatus. A. fumigatus biofilm
formation occurs in vitro and in vivo and is associated with physiological changes. In this …

Linking calcium signaling and mitochondrial function in fungal drug resistance

P Bowyer, MJ Bromley… - Proceedings of the …, 2020 - National Acad Sciences
The host range for Aspergillus fumigatus is wide, including mammals, aves, and insecta
(stonebrood). This is linked to the significant adaptability of this important fungal pathogen. It …