A single mutation attenuates both the transcription termination and RNA-dependent RNA polymerase activity of T7 RNA polymerase

H Wu, T Wei, B Yu, R Cheng, F Huang, X Lu, Y Yan… - RNA biology, 2021 - Taylor & Francis
Transcription termination is one of the least understood processes of gene expression. As
the prototype model for transcription studies, the single-subunit T7 RNA polymerase (RNAP) …

[HTML][HTML] Recent advances in understanding transcription termination by RNA polymerase II

TJ Loya, D Reines - F1000Research, 2016 - ncbi.nlm.nih.gov
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …

Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner

CM Nemec, F Yang, JM Gilmore… - Proceedings of the …, 2017 - National Acad Sciences
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II)
orchestrates dynamic recruitment of specific cellular machines during different stages of …

[HTML][HTML] Genome-wide mapping of yeast RNA polymerase II termination

P Schaughency, J Merran, JL Corden - PLoS genetics, 2014 - journals.plos.org
Yeast RNA polymerase II (Pol II) terminates transcription of coding transcripts through the
polyadenylation (pA) pathway and non-coding transcripts through the non-polyadenylation …

High‐resolution transcription maps reveal the widespread impact of roadblock termination in yeast

T Candelli, D Challal, JB Briand, J Boulay… - The EMBO …, 2018 - embopress.org
Transcription termination delimits transcription units but also plays important roles in limiting
pervasive transcription. We have previously shown that transcription termination occurs …

[PDF][PDF] Integrator-dependent and allosteric/intrinsic mechanisms ensure efficient termination of snRNA transcription

L Davidson, L Francis, JD Eaton, S West - Cell reports, 2020 - cell.com
Many RNA polymerases terminate transcription using allosteric/intrinsic mechanisms,
whereby protein alterations or nucleotide sequences promote their release from DNA. RNA …

[PDF][PDF] Genome-wide analysis of RNA polymerase II termination at protein-coding genes

C Baejen, J Andreani, P Torkler, S Battaglia, B Schwalb… - Molecular cell, 2017 - cell.com
At the end of protein-coding genes, RNA polymerase (Pol) II undergoes a concerted
transition that involves 3′-processing of the pre-mRNA and transcription termination. Here …

[HTML][HTML] Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo

K Rijal, RJ Maraia - PLoS genetics, 2016 - journals.plos.org
The ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation
is critical for abundant tRNA production during cellular proliferation, development and …

[HTML][HTML] Dismantling promoter-driven RNA polymerase II transcription complexes in vitro by the termination factor Rat1

EL Pearson, CL Moore - Journal of Biological Chemistry, 2013 - ASBMB
Proper RNA polymerase II (Pol II) transcription termination is essential to generate stable
transcripts, to prevent interference at downstream loci, and to recycle Pol II back to the …

[HTML][HTML] Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII

A Wagschal, E Rousset, P Basavarajaiah, X Contreras… - Cell, 2012 - cell.com
Transcription elongation is increasingly recognized as an important mechanism of gene
regulation. Here, we show that microprocessor controls gene expression in an RNAi …