A single mutation attenuates both the transcription termination and RNA-dependent RNA polymerase activity of T7 RNA polymerase
H Wu, T Wei, B Yu, R Cheng, F Huang, X Lu, Y Yan… - RNA biology, 2021 - Taylor & Francis
Transcription termination is one of the least understood processes of gene expression. As
the prototype model for transcription studies, the single-subunit T7 RNA polymerase (RNAP) …
the prototype model for transcription studies, the single-subunit T7 RNA polymerase (RNAP) …
[HTML][HTML] Recent advances in understanding transcription termination by RNA polymerase II
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …
chain extension and dissociates from the chromatin template, thereby defining the end of the …
Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II)
orchestrates dynamic recruitment of specific cellular machines during different stages of …
orchestrates dynamic recruitment of specific cellular machines during different stages of …
[HTML][HTML] Genome-wide mapping of yeast RNA polymerase II termination
P Schaughency, J Merran, JL Corden - PLoS genetics, 2014 - journals.plos.org
Yeast RNA polymerase II (Pol II) terminates transcription of coding transcripts through the
polyadenylation (pA) pathway and non-coding transcripts through the non-polyadenylation …
polyadenylation (pA) pathway and non-coding transcripts through the non-polyadenylation …
High‐resolution transcription maps reveal the widespread impact of roadblock termination in yeast
T Candelli, D Challal, JB Briand, J Boulay… - The EMBO …, 2018 - embopress.org
Transcription termination delimits transcription units but also plays important roles in limiting
pervasive transcription. We have previously shown that transcription termination occurs …
pervasive transcription. We have previously shown that transcription termination occurs …
[PDF][PDF] Integrator-dependent and allosteric/intrinsic mechanisms ensure efficient termination of snRNA transcription
L Davidson, L Francis, JD Eaton, S West - Cell reports, 2020 - cell.com
Many RNA polymerases terminate transcription using allosteric/intrinsic mechanisms,
whereby protein alterations or nucleotide sequences promote their release from DNA. RNA …
whereby protein alterations or nucleotide sequences promote their release from DNA. RNA …
[PDF][PDF] Genome-wide analysis of RNA polymerase II termination at protein-coding genes
At the end of protein-coding genes, RNA polymerase (Pol) II undergoes a concerted
transition that involves 3′-processing of the pre-mRNA and transcription termination. Here …
transition that involves 3′-processing of the pre-mRNA and transcription termination. Here …
[HTML][HTML] Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo
The ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation
is critical for abundant tRNA production during cellular proliferation, development and …
is critical for abundant tRNA production during cellular proliferation, development and …
[HTML][HTML] Dismantling promoter-driven RNA polymerase II transcription complexes in vitro by the termination factor Rat1
EL Pearson, CL Moore - Journal of Biological Chemistry, 2013 - ASBMB
Proper RNA polymerase II (Pol II) transcription termination is essential to generate stable
transcripts, to prevent interference at downstream loci, and to recycle Pol II back to the …
transcripts, to prevent interference at downstream loci, and to recycle Pol II back to the …
[HTML][HTML] Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII
A Wagschal, E Rousset, P Basavarajaiah, X Contreras… - Cell, 2012 - cell.com
Transcription elongation is increasingly recognized as an important mechanism of gene
regulation. Here, we show that microprocessor controls gene expression in an RNAi …
regulation. Here, we show that microprocessor controls gene expression in an RNAi …