After transcription termination, cellular RNA polymerases (RNAPs) are occasionally trapped
on DNA, impounded in an undefined post-termination complex (PTC), limiting the free RNAP …

Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3′
end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the …

We have shown previously that a T 10 peptide nucleic acid (PNA) bound to the
transcriptional terminator of a Saccharomyces cerevisiae tDNA Ile (TAT) gene arrests …

Background Making the correct choice between transcription elongation and transcription
termination is essential to the function of RNA polymerase II, and fundamental to gene …

Termination of the RNA polymerase III (Pol III)-mediated transcription requires the
conversion of an elongation complex (EC) to a pre-termination complex (PTC) on poly …

Eukaryotic initiator tRNA (tRNAi) contains several highly conserved unique sequence
features, but their importance in accurate start codon selection was unknown. Here we show …

During transcription, RNA polymerase II (RNAPII) must select the correct nucleotide,
catalyze its addition to the growing RNA transcript, and move stepwise along the DNA until a …

How eukaryotic RNA polymerases switch from elongation to termination is unknown. Pol III
subunits Rpc53 and Rpc37 (C53/37) form a heterodimer homologous to TFIIFβ/α. C53/37 …

During transcription termination by RNA polymerase II on protein-coding genes, the nuclear
5′ exonuclease Rat1/Xrn2 degrades the nascent transcript downstream from the …

Most eukaryotic genes are transcribed by RNA polymerase II (Pol II), including those that
produce mRNAs and many noncoding functional RNAs. Proper expression of these genes …