Isoginkgetin treatment attenuated lipopolysaccharide-induced monoamine neurotransmitter deficiency and depression-like behaviors through downregulating p38/NF …

P Li, F Zhang, Y Li, C Zhang, Z Yang… - Journal of …, 2021 - journals.sagepub.com
Background: Microglia activation-induced neuroinflammation may contribute to the etiology
of depression. Podocarpus nagi containing high concentration of isoginkgetin could …

Molecular and biological functions of resveratrol in psychiatric disorders: a review of recent evidence

M Shayganfard - Cell & bioscience, 2020 - Springer
Mental disorders including depression, anxiety, schizophrenia, autism spectrum disorders,
bipolar and etc. have a considerable proportion of global disorder burden. Many nutritional …

Raw and wine processed Schisandra chinensis attenuate anxiety like behavior via modulating gut microbiota and lipid metabolism pathway

Y Song, B Shan, S Zeng, J Zhang, C Jin, Z Liao… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance In traditional Chinese medicine, the fruit of
Schisandra chinensis (Turcz.) Baill (SC) is used to treat various nervous system diseases …

[HTML][HTML] Protective effect of water extracted Spirulina maxima on glutamate-induced neuronal cell death in mouse hippocampal HT22 cell

HY Lee, GH Ryu, WY Choi, WS Yang… - Pharmacognosy …, 2018 - ncbi.nlm.nih.gov
Materials and Methods: S. maxima was extracted in water and contain of phycocyanin was
identified by high-performance liquid chromatography. Cell viability test was performed with …

Ameliorative effect of fisetin against lipopolysaccharide and restraint stress-induced behavioral deficits via modulation of NF-κB and IDO-1

P Choubey, M Kwatra, SN Pandey, D Kumar… - …, 2019 - Springer
Background Fisetin, a plant active polyphenol, is well known for its antioxidant and free
radical scavenging activities. The present study was designed to explore the detailed …

Alternative therapy of psychosis: Potential phytochemicals and drug targets in the management of schizophrenia

A Saleem, MF Akhtar - Frontiers in pharmacology, 2022 - frontiersin.org
Schizophrenia is a chronic mental and behavioral disorder characterized by clusters of
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …

Crocin, a natural product attenuates lipopolysaccharide-induced anxiety and depressive-like behaviors through suppressing NF-kB and NLRP3 signaling pathway

L Zhang, R Previn, L Lu, RF Liao, Y Jin, RK Wang - Brain research bulletin, 2018 - Elsevier
Depression is one of the foremost psychological illness which is closely leagued with
inflammation. Crocin is a natural product that exhibits both anti-inflammatory and anti …

Saffron extract attenuates neuroinflammation in rmTBI mouse model by suppressing NLRP3 inflammasome activation via SIRT1

MJ Shaheen, AM Bekdash, HA Itani, JM Borjac - PLoS One, 2021 - journals.plos.org
Traumatic brain injury (TBI) remains a major cause of morbidity and disability worldwide and
a healthcare burden. TBI is an important risk factor for neurodegenerative diseases …

Potential therapeutic antipsychotic effects of Naringin against ketamine-induced deficits in rats: involvement of Akt/GSK-3β and Wnt/β-catenin signaling pathways

MY George, ET Menze, A Esmat, MG Tadros… - Life sciences, 2020 - Elsevier
Aim Schizophrenia is a chronic, disabling and one of the major neurological illnesses
affecting nearly 1% of the global population. Currently available antipsychotic medications …

Neuroinflammation in schizophrenia: the key role of the WNT/β-catenin pathway

A Vallée - International Journal of Molecular Sciences, 2022 - mdpi.com
Schizophrenia is a very complex syndrome involving widespread brain multi-
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …