Background Although the genomes of monozygotic twins are practically identical, their
methylomes may evolve divergently throughout their lifetime as a consequence of factors …

Background Monozygotic twins have long been studied to estimate heritability and explore
epigenetic influences on phenotypic variation. The phenotypic and epigenetic similarities of …

Monozygotic twins share identical genomic DNA and are indistinguishable using
conventional genetic markers. Increasing evidence indicates that monozygotic twins are …

DNA methylation patterns are characterized by highly conserved developmental programs,
but allow for divergent gene expression resulting from stochastic epigenetic drift or divergent …

Comparison between groups of monozygotic (MZ) and dizygotic (DZ) twins enables an
estimation of the relative contribution of genetic and shared and nonshared environmental …

Background Low birth weight is associated with an increased adult metabolic disease risk. It
is widely discussed that poor intra-uterine conditions could induce long-lasting epigenetic …

Genetic-epidemiological studies on monozygotic (MZ) twins have been used for decades to
tease out the relative contributions of genes and the environment to a trait. Phenotypic …

Background The extent to which development-and age-associated epigenetic changes are
influenced by genetic, environmental and stochastic factors remains to be discovered. Twins …

Twin studies have provided the basis for genetic and epidemiological studies in human
complex traits,. As epigenetic factors can contribute to phenotypic outcomes, we conducted …

Background DNA methylation levels will be important for detection of epigenetic effects.
However, there are few reports showing sex-related differences in the sensitivity to DNA …