Background: Obesity before pregnancy is associated with impaired metabolic status of the
mother and the offspring later in life. These adverse effects have been attributed to …

Obese women, on average, give birth to babies with high fat mass. Placental lipid
metabolism alters fetal lipid delivery, potentially moderating neonatal adiposity, yet how it is …

Objective Maternal obesity increases the incidence of excess adiposity in newborns,
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …

Placentas of obese women have low mitochondrial β-oxidation of fatty acids (FA) and
accumulate lipids in late pregnancy. This creates a lipotoxic environment, impairing …

Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated
with pregnancy complications such as preeclampsia and gestational diabetes, and offspring …

OBJECTIVE: Changes in metabolic homeostasis in pregnant diabetic women are potential
determinants of increased adiposity of the fetus. The aim of this study was to characterize …

The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …

Maternal obesity is associated with an increased risk of obesity and metabolic disease in
offspring. Increasing evidence suggests that the placenta plays an active role in fetal …

Pregestational obesity is a significant risk factor for adverse pregnancy outcomes. Maternal
obesity is associated with a specific proinflammatory, endocrine and metabolic phenotype …