Advances in X-ray computed tomography (CT) has enabled soft-tissue X-ray imaging with
improved contrast and resolution. As a result, non-destructive X-ray 3D virtual histology is …

Advances in laboratory-based X-ray computed tomography (CT) have enabled X-ray 3D
virtual histology. This method shows a great potential as a complementary technique to …

Histological investigations are indispensable with regards to the identification of structural
tissue details but are limited to two-dimensional images, which are often visualized in one …

Videos Video 1 A video going through the Z stack in single slices. This is a cross-sectional
view of the XRH image stack along the XY plane. XRH datasets are normally oriented …

Background The University of Southampton, in collaboration with the University Hospital
Southampton (UHS) NHS Foundation Trust and industrial partners, has been at the forefront …

Histology and immunohistochemistry of thin tissue sections have been the standard
diagnostic procedure in many diseases for decades. This method is highly specific for …

Examination of histological or immunohistochemically stained 2D sections of embedded
tissue is one of the most frequently used tools in biomedical research and clinical routine …

The application of 3D X-ray imaging for biological samples (eg biopsies) to gain a deeper
understanding of microscopic structures on a (sub) cellular level is restricted by the weak …

Propagation-based X-ray phase-contrast imaging (PBI) is a powerful nondestructive imaging
technique that can reveal the internal detailed structures in weakly absorbing samples …

Malignant diseases are characterized by a critical trait known as invasiveness, where tumor
cells tend to spread from the primary tissue layer into surrounding healthy tissues and …