Personalized dendritic cell-based tumor immunotherapy

N Janikashvili, N Larmonier, E Katsanis - Immunotherapy, 2010 - Future Medicine
Advances in the understanding of the immunoregulatory functions of dendritic cells (DCs) in
animal models and humans have led to their exploitation as anticancer vaccines. Although …

Modulation of antitumor responses by dendritic cells

J Vieweg, A Jackson - Springer seminars in immunopathology, 2005 - Springer
The discovery that dendritic cells (DC) play a key role in regulating antitumor immunity has
prompted considerable efforts in developing DC-based cancer vaccines for use in clinical …

Trial watch: Dendritic cell-based interventions for cancer therapy

L Galluzzi, L Senovilla, E Vacchelli, A Eggermont… - …, 2012 - Taylor & Francis
Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Dendritic cell-based cancer vaccination: quo vadis?

M Dauer, M Schnurr, A Eigler - Expert Review of Vaccines, 2008 - Taylor & Francis
Dendritic cells (DCs) play a central role in the initiation and regulation of primary immune
responses. DCs loaded with tumor-associated antigens induce anti-tumoral cytotoxic T cells …

Therapeutic Dendritic Cell− Based Cancer Vaccines: The State of the Art

MM Strioga, T Felzmann, DJ Powell Jr… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Dendritic cells (DCs) are the most potent professional antigen-presenting cells, capable of
initiating proper adaptive immune responses. Although tumor-infiltrating DCs are able to …

Dendritic cells for specific cancer immunotherapy

N Meidenbauer, R Andreesen, A Mackensen - 2001 - degruyter.com
The characterization of tumorassociated antigens recognized by human T lymphocytes in a
major histocompatibility complex (MHC) restricted fashion has opened new possibilities for …

Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives

J Constantino, C Gomes, A Falcão, MT Cruz… - Translational …, 2016 - Elsevier
Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …

Rationale for the combination of dendritic cell-based vaccination approaches with chemotherapy agents

I Truxova, M Hensler, P Skapa, MJ Halaska… - International Review of …, 2017 - Elsevier
Owing to their central role in the initiation and regulation of antitumor immunity, dendritic
cells (DCs) have been widely tested for use in cancer immunotherapy. Despite several …

Directing dendritic cell immunotherapy towards successful cancer treatment

RL Sabado, N Bhardwaj - Immunotherapy, 2010 - Future Medicine
The use of dendritic cells (DCs) for tumor immunotherapy represents a powerful approach
for harnessing the patient's own immune system to eliminate tumor cells. However …

[HTML][HTML] Dendritic cells in cancer vaccines

P Brossart, S Wirths, W Brugger, L Kanz - Experimental hematology, 2001 - Elsevier
Dendritic cells (DC) are recognized as the most potent antigen-presenting cells with the
ability to stimulate naive resting T cells and to initiate primary immune responses …