Potentiation strategies of dendritic cell-based antitumor vaccines: combinational therapy takes the front seat

M Torabi-Rahvar, M Bozorgmehr, M Jeddi-Tehrani… - Drug discovery today, 2011 - Elsevier
Despite recent attempts to take advantage of dendritic cell (DC)-based vaccines for cancer
immunotherapy, the results of clinical studies have been disappointing. This is mainly as a …

Dendritic cells: are they clinically relevant?

K Palucka, H Ueno, L Roberts, J Fay… - The Cancer …, 2010 - journals.lww.com
Cancer vaccines have undergone a renaissance because of recent clinical trials showing
promising immunologic data and some clinical benefit to patients. Current trials exploiting …

Dendritic cell engineering for tumor immunotherapy: from biology to clinical translation

A Bhargava, D Mishra, S Banerjee, PK Mishra - Immunotherapy, 2012 - Taylor & Francis
Dendritic cells (DCs) are the most potent APCs, with the ability to orchestrate a repertoire of
immune responses. DCs play a pivotal role in the initiation, programming and regulation of …

Trial watch: dendritic cell vaccination for cancer immunotherapy

J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Presentation of tumour antigens by dendritic cells and challenges faced

NC Robson, S Hoves, E Maraskovsky… - Current opinion in …, 2010 - Elsevier
The use of dendritic cells (DCs) for the generation of anti-tumour immunity has been the
focus of a vast array of scientific and clinical studies. The ability of DCs to present protein …

[HTML][HTML] Dendritic cell-based immunotherapy

RL Sabado, S Balan, N Bhardwaj - Cell research, 2017 - nature.com
Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …

Dendritic cells as cancer therapeutics

CE Bryant, S Sutherland, B Kong… - Seminars in Cell & …, 2019 - Elsevier
The ability of immune therapies to control cancer has recently generated intense interest.
This therapeutic outcome is reliant on T cell recognition of tumour cells. The natural function …

Dendritic cell-based therapeutic cancer vaccines: what we have and what we need

P Kalinski, J Urban, R Narang, E Berk… - Future …, 2009 - Taylor & Francis
Therapeutic cancer vaccines rely on the immune system to eliminate tumor cells. In contrast
to chemotherapy or passive (adoptive) immunotherapies with antibodies or ex vivo …

Dendritic cell-based vaccines: from mouse models to clinical cancer immunotherapy

MWJ Schreurs, AAO Eggert, CJA Punt… - Critical Reviews™ in …, 2000 - dl.begellhouse.com
ABSTRACT B and T lymphocytes are the effectors of specific immunity. However, their
function is critically dependent on dendritic cells (DC). DC are professional antigen …

Dendritic cell-based vaccines and therapies for cancer

T Tatsumi, WJ Storkus - Expert Opinion on Biological Therapy, 2002 - Taylor & Francis
Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs), and
are capable of stimulating naive T cells and driving primary immune responses. Due to this …