Novel perspectives on dendritic cell-based immunotherapy of cancer

I Bonaccorsi, G Pezzino, B Morandi, G Ferlazzo - Immunology Letters, 2013 - Elsevier
Advances in immunobiology knowledge as well as in cell culture processes that generate
large numbers of purified and functionally mature dendritic cells (DCs) have raised the …

Cancer vaccines for established cancer: how to make them better?

DM Andrews, E Maraskovsky… - Immunological reviews, 2008 - Wiley Online Library
If one envisions dendritic cells (DCs) as nature's adjuvant, then it is easy to predict that they
would be advantageous for cancer immunotherapy. Advances in culture processes that …

Dendritic cells in cancer immunotherapy: vaccines and combination immunotherapies

P Kalinski, R Muthuswamy, J Urban - Expert review of vaccines, 2013 - Taylor & Francis
Dendritic cells (DCs) are specialized immunostimulatory cells involved in the induction and
regulation of immune responses. The feasibility of large-scale ex vivo generation of DCs …

[HTML][HTML] Dendritic cell-targeted approaches to modulate immune dysfunction in the tumor microenvironment

A Gallois, N Bhardwaj - Frontiers in immunology, 2013 - frontiersin.org
There has been enormous progress this past decade in the understanding of the biology of
dendritic cells (DCs) along with increasing attention for the development of novel dendritic …

Dendritic cells in cancer immunotherapy

A Vulink, KJ Radford, C Melief, DNJ Hart - Advances in cancer research, 2008 - Elsevier
Since their discovery, there has been significant progress in the understanding of dendritic
cell (DC) biology. Their capacity for priming an immune response against pathogens and …

Dendritic cells: a critical player in cancer therapy?

AK Palucka, H Ueno, J Fay… - Journal of …, 2008 - journals.lww.com
Cancer immunotherapy seeks to mobilize a patient's immune system for therapeutic benefit.
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …

Reengineering dendritic cell‐based anti‐cancer vaccines

GK Koski, PA Cohen, RE Roses, S Xu… - Immunological …, 2008 - Wiley Online Library
Despite initial enthusiasm, dendritic cell (DC)‐based anti‐cancer vaccines have yet to live
up to their promise as one of the best hopes for generating effective anti‐tumor immunity …

Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines

V Schijns, E Tartour, J Michalek, A Stathopoulos… - Cytotherapy, 2014 - Elsevier
Tumor growth is controlled by natural antitumor immune responses alone or by augmented
immune reactivity resulting from different forms of immunotherapy, which has demonstrated …

Progress in the development of immunotherapy of cancer using ex vivo-generated dendritic cells expressing multiple tumor antigen epitopes

MA Markiewicz, WM Kast - Cancer investigation, 2004 - Taylor & Francis
Immunotherapy with tumor-associated antigen-pulsed, ex vivo-generated dendritic cells
(DCs) is a promising approach for the treatment of cancer that has shown efficacy in animal …

Naturally circulating dendritic cells to vaccinate cancer patients

KF Bol, J Tel, IJM De Vries, CG Figdor - Oncoimmunology, 2013 - Taylor & Francis
Dendritic cell-based immunotherapy is a promising strategy against cancer that appears to
be feasible, safe and to induce potent tumor-specific immune responses. The use of …