Alternating lysis and lysogeny is a winning strategy in bacteriophages due to Parrondo's paradox

KH Cheong, T Wen, S Benler… - Proceedings of the …, 2022 - National Acad Sciences
Temperate bacteriophages lyse or lysogenize host cells depending on various parameters
of infection, a key one being the ratio of the number of free viruses to the number of host …

[PDF][PDF] Phage population growth: constraints, games, adaptation

ST Abedon - Bacteriophage ecology, 2008 - ndl.ethernet.edu.et
Pick up an introductory biology textbook that describes bacteriophages. The presented
phage life cycle, often using phage λ as an example, will typically be differentiated into two …

[HTML][HTML] Optimality of the spontaneous prophage induction rate

MG Cortes, J Krog, G Balázsi - Journal of theoretical biology, 2019 - Elsevier
Lysogens are bacterial cells that have survived after genomically incorporating the DNA of
temperate bacteriophages infecting them. If an infection results in lysogeny, the lysogen …

Phenotypic stochasticity protects lytic bacteriophage populations from extinction during the bacterial stationary phase

R Gallet, T Lenormand, IN Wang - Evolution, 2012 - academic.oup.com
It is generally thought that the adsorption rate of a bacteriophage correlates positively with
fitness, but this view neglects that most phages rely only on exponentially growing bacteria …

[HTML][HTML] In silico evolution of lysis-lysogeny strategies reproduces observed lysogeny propensities in temperate bacteriophages

V Sinha, A Goyal, SL Svenningsen, S Semsey… - Frontiers in …, 2017 - frontiersin.org
Bacteriophages are the most abundant organisms on the planet and both lytic and
temperate phages play key roles as shapers of ecosystems and drivers of bacterial …

[HTML][HTML] Well-temperate phage: optimal bet-hedging against local environmental collapses

S Maslov, K Sneppen - Scientific reports, 2015 - nature.com
Upon infection of their bacterial hosts temperate phages must chose between lysogenic and
lytic developmental strategies. Here we apply the game-theoretic bet-hedging strategy …

Repeated outbreaks drive the evolution of bacteriophage communication

HM Doekes, GA Mulder, R Hermsen - Elife, 2021 - elifesciences.org
Recently, a small-molecule communication mechanism was discovered in a range of
Bacillus-infecting bacteriophages, which these temperate phages use to inform their lysis …

[PDF][PDF] Decision making by temperate phages

I Golding, S Coleman… - … of Virology, DH …, 2019 - bacteriophysics.web.illinois.edu
The defining lifestyle of most bacteriophages, analogous to the behavior of higher viruses, is
one in which infection is followed by rampant viral replication and the release of numerous …

Alternative stable states in host–phage dynamics

JS Weitz, J Dushoff - Theoretical Ecology, 2008 - Springer
Bacteriophage are ubiquitous in nature, yet many central aspects of host–phage biology
have not been integrated into mathematical models. We propose a novel model of host …

Lysis timing and bacteriophage fitness

IN Wang - Genetics, 2006 - academic.oup.com
The effect of lysis timing on bacteriophage (phage) fitness has received little theoretical or
experimental attention. Previously, the impact of lysis timing on phage fitness was studied …