Programming cell–cell communications with engineered cell origami clusters
Cells existing in the form of clusters often exhibit distinct physiological functions from their
monodispersed forms, which have a close association with tissue and organ development …
monodispersed forms, which have a close association with tissue and organ development …
DNA origami signaling units transduce chemical and mechanical signals in synthetic cells
Transmembrane proteins transmit chemical signals as well as mechanical cues. The latter is
often achieved by coupling to the cytoskeleton. The incorporation of fully engineerable …
often achieved by coupling to the cytoskeleton. The incorporation of fully engineerable …
Engineering cell surface function with DNA origami
A specific and reversible method is reported to engineer cell‐membrane function by
embedding DNA‐origami nanodevices onto the cell surface. Robust membrane …
embedding DNA‐origami nanodevices onto the cell surface. Robust membrane …
Modular DNA-origami-based nanoarrays enhance cell binding affinity through the “lock-and-key” interaction
M Mao, Z Lin, L Chen, Z Zou, J Zhang… - Journal of the …, 2023 - ACS Publications
Surface proteins of cells are generally recognized through receptor–ligand interactions
(RLIs) in disease diagnosis, but their nonuniform spatial distribution and higher-order …
(RLIs) in disease diagnosis, but their nonuniform spatial distribution and higher-order …
DNA origami: folded DNA‐nanodevices that can direct and interpret cell behavior
DNA origami is a DNA‐based nanotechnology that utilizes programmed combinations of
short complementary oligonucleotides to fold a large single strand of DNA into precise 2D …
short complementary oligonucleotides to fold a large single strand of DNA into precise 2D …
Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales
DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
DNA origami nanostructures elicit dose‐dependent immunogenicity and are nontoxic up to high doses In vivo
DNA origami (DO) nanotechnology enables the construction of precise nanostructures
capable of functionalization with small molecule drugs, nucleic acids, and proteins …
capable of functionalization with small molecule drugs, nucleic acids, and proteins …
Visualization of the cellular uptake and trafficking of DNA origami nanostructures in cancer cells
P Wang, MA Rahman, Z Zhao, K Weiss… - Journal of the …, 2018 - ACS Publications
DNA origami is a promising molecular delivery system for a variety of therapeutic
applications including cancer therapy, given its capability to fabricate homogeneous …
applications including cancer therapy, given its capability to fabricate homogeneous …
Multiscale origami structures as interface for cells
A Angelin, S Weigel, R Garrecht… - Angewandte Chemie …, 2015 - Wiley Online Library
A DNA‐based platform was developed to address fundamental aspects of early stages of
cell signaling in living cells. By site‐directed sorting of differently encoded, protein …
cell signaling in living cells. By site‐directed sorting of differently encoded, protein …
Functional DNA-based cytoskeletons for synthetic cells
The cytoskeleton is an essential component of a cell. It controls the cell shape, establishes
the internal organization, and performs vital biological functions. Building synthetic …
the internal organization, and performs vital biological functions. Building synthetic …