Energy balance is complex and regulated by neuroendocrine homeostatic mechanisms
(primarily the leptin melanocortin pathway) and non-homeostatic mechanisms (such as …

The definition of obesity is a degree of somatic overweight that affords detrimental health
consequences [1]. The majority of obesity in adulthood has its origins in childhood [2, 3, 4] …

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When discussing the causes of obesity, it is easy to point fingers at the individual.“Gluttony”
and “sloth” after all are two of the seven “deadly sins.” Obese adults and their children are …

The prevalence of pediatric obesity in the United States is nearly 17%. Most cases are
“exogenous”, resulting from excess energy intake relative to energy expenditure over a …

Obesity develops when cumulative energy intake exceeds energy expenditure. The
biological processes regulating energy balance are highly regulated. However, these …

The hypothalamus plays a key role in the regulation of body weight by balancing the intake
of food, energy expenditure, and body fat stores, as evidenced by the fact that most …

Obesity quickly is becoming the largest (figuratively and literally) public health problem, not
just in the United States, but worldwide. The Worldwatch Institute, an Internet watchdog …

Childhood obesity has become epidemic over the past 30 years. The First Law of
Thermodynamics is routinely interpreted to imply that weight gain is secondary to increased …

Based on the genetic contribution, childhood obesity can be classified into 3 groups:
common polygenic obesity, syndromic obesity, and monogenic obesity. More genetic …