Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for In Vitro and In Vivo Drug Delivery

D Aschmann, RA Knol, A Kros - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus For the delivery of drugs, different nanosized drug carriers (eg, liposomes, lipid
nanoparticles, and micelles) have been developed in order to treat diseases that afflict …

Peptide targeted lipid nanoparticles for anticancer drug delivery

TR Pearce, K Shroff, E Kokkoli - Advanced materials, 2012 - Wiley Online Library
Encapsulating anticancer drugs in nanoparticles has proven to be an effective mechanism to
alter the pharmacokinetic and pharmacodynamic profiles of the drugs, leading to clinically …

Improving peptide applications using nanotechnology

R Narayanaswamy, T Wang… - Current Topics in …, 2016 - ingentaconnect.com
Peptides are being successfully used in various fields including therapy and drug delivery.
With advancement in nanotechnology and targeted delivery carrier systems, suitable …

Chemistry and art of developing lipid nanoparticles for biologics delivery: focus on development and scale-up

R John, J Monpara, S Swaminathan, R Kalhapure - Pharmaceutics, 2024 - mdpi.com
Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines

M Puccetti, M Pariano, A Schoubben… - Journal of Pharmacy …, 2024 - academic.oup.com
Biological membrane-engineered lipid nanoparticles (LNP) have shown enormous potential
as vehicles for drug delivery due to their outstanding biomimetic properties. To make these …

[HTML][HTML] Nanoparticles modified with cell-penetrating peptides: Conjugation mechanisms, physicochemical properties, and application in cancer diagnosis and …

I Gessner, I Neundorf - International journal of molecular sciences, 2020 - mdpi.com
Based on their tunable physicochemical properties and the possibility of producing cell-
specific platforms through surface modification with functional biomolecules, nanoparticles …

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

B Bogaert, F Sauvage, R Guagliardo, C Muntean… - Journal of Controlled …, 2022 - Elsevier
Since the recent clinical approval of siRNA-based drugs and COVID-19 mRNA vaccines, the
potential of RNA therapeutics for patient healthcare has become widely accepted. Lipid …

Lipid-like self-assembling peptide nanovesicles for drug delivery

DG Fatouros, DA Lamprou, AJ Urquhart… - … applied materials & …, 2014 - ACS Publications
Amphiphilic self-assembling peptides are functional materials, which, depending on the
amino acid sequence, the peptide length, and the physicochemical conditions, form a variety …

Peptide-based stealth nanoparticles for targeted and pH-triggered delivery

A Ranalli, M Santi, L Capriotti, V Voliani… - Bioconjugate …, 2017 - ACS Publications
Stealth agents are extensively investigated as a means by which to prolong nanostructure
residence time in the bloodstream by avoiding uptake by the reticuloendothelial system …

Delivery of membrane impermeable cargo into CHO cells by peptide nanoparticles targeted by a protein corona

C Dittrich, CJ Burckhardt, G Danuser - Biomaterials, 2012 - Elsevier
Nanocarriers can fulfill essential functions in the stabilization and delivery of drugs: they
prevent solubility issues and degradation, reduce side effects and modify the …