In the hours to days after intracerebral hemorrhage (ICH), there is an inflammatory response
within the brain characterized by the infiltration of peripheral neutrophils and macrophages …

Background Increased age is a major risk factor for stroke incidence, post-ischemic mortality,
and severe and long-term disability. Stroke outcome is considerably influenced by post …

Neuroinflammation is associated with glial activation following a variety of brain injuries,
including stroke. While activation of perilesional astrocytes and microglia following ischemic …

Intracerebral hemorrhage (ICH) is a major health concern, with high rates of mortality and
morbidity and no highly effective clinical interventions. Basic research in animal models of …

Aged microglia display augmented inflammatory activity after neural injury. Although aging
is a risk factor for poor outcome after brain insults, the precise impact of aging-related …

Background and Purpose—In cerebral stroke, the overall mortality rate of older individuals is
higher than that of younger individuals. We therefore investigated aging-related changes in …

OBJECTIVE: We sought to analyze the regional concentrations of proinflammatory cytokines
in the acute period of intracerebral hemorrhage (ICH) and to test the hypothesis that ICH is …

Background Aging is not just a risk factor of stroke, but it has also been associated with poor
recovery. It is known that stroke-induced neurogenesis is reduced but maintained in the …

Background and Purpose: Spontaneous intracerebral hemorrhage (sICH) is a common form
of hemorrhagic stroke, with high mortality and morbidity. Pathophysiological mechanisms in …

Intracerebral hemorrhage (ICH) is associated with stroke and head trauma. Different
experimental models are used, but it is unclear to what extent the tissue responses are …