Hesperidin is a flavonoid glycoside that is frequently found in citrus fruits. Our group have
demonstrated that hesperidin has neuroprotective effect in 6-hydroxydopamine (6-OHDA) …

The mechanisms underlying the neuroprotective effects of hesperidin in a murine model of
PD are not fully elucidated. The current study was carried out to investigate the ability of …

Parkinson's disease (PD) is a common, chronic, and debilitating neurodegenerative disorder
characterized by progressive loss of nigrostriatal dopaminergic neurons due to unknown …

Parkinson's disease (PD) is a neurodegenerative disorder due to loss of dopaminergic
neurons in the substantia nigra pars compacta (SNC). PD finally leads to incapacitating …

Objective Parkinson's disease (PD) may be caused by the interaction of a number of factors,
including genetics, toxins, oxidative stress, mitochondrial abnormalities, and aging. Studies …

The pathological alterations of Parkinson's disease (PD) predominantly manifest as a loss of
dopaminergic neurons in the substantia nigra, which may be caused by oxidative stress …

Quercetin, one of the major flavonoids in plants, has been recently reported to have
neuroprotective effects against neurodegenerative processes. However, since the molecular …

The role of mitochondrial dysfunction and oxidative stress has been well-documented in
Alzheimer's disease (AD). Bioflavonoids are being utilised as neuroprotectants in the …

Amyloid-β (Aβ) is known to exert cytotoxic effects by inducing mitochondrial dysfunction.
Additionally, the mitochondrial voltage-dependent anion channel 1 (VDAC1), which is …

Mounting evidence suggests that mitochondrial dysfunction and impaired mitophagy lead to
Parkinson's disease (PD). Quercetin, one of the most abundant polyphenolic flavonoids …