Exploring joint patterns of brain structure and function in inflammatory bowel diseases using multimodal data fusion

AK Thomann, MM Schmitgen, D Kmuche… - …, 2021 - Wiley Online Library
Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

[HTML][HTML] Altered structural covariance and functional connectivity of the insula in patients with Crohn's disease

S Zhang, F Chen, J Wu, C Liu, G Yang… - … imaging in medicine …, 2022 - ncbi.nlm.nih.gov
Background Crohn's disease (CD) is a clinically chronic inflammatory bowel disease, which
has been shown to be closely related to the brain-gut axis dysfunction. Although traditionally …

Disruption of Periaqueductal Gray-default Mode Network Functional Connectivity in Patients with Crohn's Disease with Abdominal Pain

F Chen, S Zhang, P Li, K Xu, C Liu, B Geng, R Piao… - Neuroscience, 2023 - Elsevier
Abdominal pain in Crohn's disease (CD) has been known to be associated with changes in
the central nervous system. The periaqueductal gray (PAG) plays a well-established role in …

[HTML][HTML] Altered markers of brain development in Crohn's Disease with extraintestinal manifestations–a pilot study

AK Thomann, PA Thomann, RC Wolf, D Hirjak… - PloS one, 2016 - journals.plos.org
Background and Objective Alterations of brain morphology in Crohn's disease have been
reported, but data is scarce and heterogenous and the possible impact of disease …

Alterations in Brain Grey Matter Structures in Patients With Crohn's Disease and Their Correlation With Psychological Distress☆

CH Bao, P Liu, HR Liu, LY Wu, Y Shi… - Journal of Crohn's …, 2015 - academic.oup.com
Abstract Background: Whether Crohn's disease [CD] is correlated with brain structural
changes is unclear. This study examined changes in grey matter [GM] structures in CD …

[HTML][HTML] Differences in brain gray matter volume in patients with Crohn's disease with and without abdominal pain

C Bao, P Liu, Y Shi, L Wu, X Jin, X Zeng, J Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Increasing evidence indicates that abnormal pain processing is present in the central
nervous system of patients with Crohn's disease (CD). The purposes of this study were to …

The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease

J Wang, G Liu, K Xu, K Ai, W Huang… - Human Brain …, 2023 - Wiley Online Library
A growing body of evidence from neuroimaging studies suggests that inflammatory bowel
disease (IBD) is associated with functional and structural alterations in the central nervous …

[HTML][HTML] Brain changes detected by functional magnetic resonance imaging and spectroscopy in patients with Crohn's disease

K Lv, YH Fan, L Xu, MS Xu - World journal of gastroenterology, 2017 - ncbi.nlm.nih.gov
Crohn's disease (CD) is a chronic, non-specific granulomatous inflammatory disorder that
commonly affects the small intestine and is a phenotype of inflammatory bowel disease …

[HTML][HTML] Altered brain structural connectivity in patients with longstanding gut inflammation is correlated with psychological symptoms and disease duration

J Turkiewicz, RR Bhatt, H Wang, P Vora, B Krause… - NeuroImage: Clinical, 2021 - Elsevier
Objective We aimed to identify differences in network properties of white matter
microstructure between asymptomatic ulcerative colitis (UC) participants who had a history …

[HTML][HTML] Alterations of regional homogeneity in Crohn's disease with psychological disorders: a resting-state fMRI study

M Huang, X Li, W Fan, J Li, L Zhu, P Lei, L Wu… - Frontiers in …, 2022 - frontiersin.org
Abnormal psychological processing in the central nervous system has been found in
Crohn's disease (CD) patients. Resting-state functional magnetic resonance images of 57 …