Long‐term outcomes after seton placement for perianal fistulas with and without Crohn's disease

MAK Motamedi, S Serahati, L Rajendran… - Colorectal …, 2021 - Wiley Online Library
Abstract Aim Perianal sepsis in Crohn's disease (CD) fistulas is managed with antibiotics
and surgical drainage; a noncutting seton is used for an identified transsphincteric fistula …

[HTML][HTML] Evaluation of a seton procedure combined with infliximab therapy (early vs. late) in perianal fistula with Crohn disease

M Jeon, K Song, J Koo, S Kim - Annals of Coloproctology, 2019 - ncbi.nlm.nih.gov
Purpose We assessed the clinical outcomes of a seton procedure combined with early
versus late institution of infliximab (IFX) therapy. Methods This retrospective study comprised …

Clinical advantages of combined seton placement and infliximab maintenance therapy for perianal fistulizing Crohn's disease: when and how were the seton drains …

S Tanaka, K Matsuo, T Sasaki, M Nakano… - Hepato …, 2010 - europepmc.org
Results For all patients average number of inserted drains was 4.5 and the average number
of infliximab infusions was 9.4 times. The mean follow-up period was 12.1 months. A …

Treatment of perianal fistulas in Crohn's disease, seton versus anti-TNF versus surgical closure following anti-TNF [PISA]: a randomised controlled trial

KA Wasmann, EJ de Groof… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims Most patients with perianal Crohn's fistula receive medical
treatment with anti-tumour necrosis factor [TNF], but the results of anti-TNF treatment have …

Surgical management of fistulating perianal Crohn's disease: a UK survey

MJ Lee, N Heywood, PM Sagar, SR Brown… - Colorectal …, 2017 - Wiley Online Library
Aim Around one‐third of patients with Crohn's disease are affected by Crohn's fistula‐in‐ano
(p CD). It typically follows a chronic course and patients undergo long‐term medical and …

Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial

EJ de Groof, CJ Buskens, CY Ponsioen… - Trials, 2015 - Springer
Background Currently there is no guideline for the treatment of patients with Crohn's disease
and high perianal fistulas. Most patients receive anti-TNF medication, but no long-term …

The role of multimodal treatment in Crohn′ s disease patients with perianal fistula: a multicentre retrospective cohort study

S Sebastian, C Black, D Pugliese… - Alimentary …, 2018 - Wiley Online Library
Summary Background Treatment paradigms for Crohn′ s disease with perianal fistulae
(CD‐pAF) are evolving. Aims To study the impact of multimodality treatment in CD‐pAF on …

Treatment of perianal fistula in Crohn's disease: a systematic review and meta‐analysis comparing seton drainage and anti‐tumour necrosis factor treatment

EJ de Groof, S Sahami, C Lucas… - Colorectal …, 2016 - Wiley Online Library
Aim The introduction of anti‐tumour necrosis factor (anti‐TNF; infliximab and adalimumab)
has changed the management of Crohn's perianal fistula from almost exclusively surgical …

The results of seton drainage combined with anti‐TNF α therapy for anal fistula in Crohn's disease

A Haennig, G Staumont, B Lepage, P Faure… - Colorectal …, 2015 - Wiley Online Library
Aim Combined infliximab and sphincter‐sparing surgery can be effective in perianal fistula
associated with Crohn's disease (CD). This study aimed to assess the efficacy of local …

[HTML][HTML] Surgical options for perianal fistula in patients with Crohn's disease: A comparison of seton placement, fistulotomy, and stem cell therapy

MY Park, YS Yoon, HE Kim, JL Lee, IJ Park… - Asian Journal of …, 2021 - Elsevier
Objective This study was designed to assess the demographic characteristics of patients
with Crohn's perianal fistula (CPF) who were treated at a tertiary referral institution. Surgical …