The global human population has recently experienced an increase in life expectancy with a
mounting concern about the steady rise in the incidence of age-associated chronic diseases …

The objective of this review is to provide an overview of intermittent fasting regimens,
summarize the evidence on the health benefits of intermittent fasting, and discuss …

Obesity remains a major public health concern and intermittent fasting is a popular strategy
for weight loss, which may present independent health benefits. However, the number of diet …

Humans in modern societies typically consume food at least three times daily, while
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …

Obesity and overweight are contributing factors to chronic disease. Lifestyle management,
which incorporates advice on moderate daily caloric restriction (CR) and physical activity to …

Most animals alternate periods of feeding with periods of fasting often coinciding with sleep.
Upon> 24 hr of fasting, humans, rodents, and other mammals enter alternative metabolic …

Given the ongoing strain that the obesity epidemic has placed on public health outcomes,
new and effective approaches to weight control are needed. One approach to improving …

Aging is associated with a host of biological changes that contribute to a progressive decline
in cognitive and physical function, ultimately leading to a loss of independence, and …

METHODS As noted above, we present a brief background of this considerable literature on
intermittent fasting in animal models to provide context to the translational research that has …

Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …