Microbiota-derived metabolites as drivers of gut–brain communication

H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen… - Gut …, 2022 - Taylor & Francis
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Adult hippocampal neurogenesis is regulated by the microbiome

ES Ogbonnaya, G Clarke… - Biological …, 2015 - biologicalpsychiatryjournal.com
Accumulating evidence suggests that the microbiota plays a key role in the brain and
behavior (1–4). Alterations in the gut microbiota-brain axis have been implicated in stress …

[HTML][HTML] The microbiota–gut–brain axis and alzheimer disease. From dysbiosis to neurodegeneration: Focus on the central nervous system glial cells

MG Giovannini, D Lana, C Traini… - Journal of Clinical …, 2021 - mdpi.com
The microbiota–gut system can be thought of as a single unit that interacts with the brain via
the “two-way” microbiota–gut–brain axis. Through this axis, a constant interplay mediated by …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Microbiome in brain function and mental health

PJ Kennedy, AB Murphy, JF Cryan, PR Ross… - Trends in Food Science …, 2016 - Elsevier
Background Over recent years it has become evident that the physiological influence of the
gut microbiota extends beyond the periphery to the central nervous system (CNS). Current …

[HTML][HTML] More than a gut feeling: the microbiota regulates neurodevelopment and behavior

JF Cryan, TG Dinan - Neuropsychopharmacology, 2015 - ncbi.nlm.nih.gov
The realization of the importance of the gut microbiota in health and disease has been one
of the most exciting areas in biomedical research over the past 5 years. We are teeming with …

Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice

A Burokas, S Arboleya, RD Moloney, VL Peterson… - Biological …, 2017 - Elsevier
Background The realization that the microbiota-gut-brain axis plays a critical role in health
and disease, including neuropsychiatric disorders, is rapidly advancing. Nurturing a …

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

M Crumeyrolle-Arias, M Jaglin, A Bruneau… - …, 2014 - Elsevier
Background and aims Establishment of the gut microbiota is one of the most important
events in early life and emerging evidence indicates that the gut microbiota influences …

Modulation of gut microbiota–brain axis by probiotics, prebiotics, and diet

X Liu, S Cao, X Zhang - Journal of agricultural and food chemistry, 2015 - ACS Publications
There exists a bidirectional communication system between the gastrointestinal tract and the
brain. Increasing evidence shows that gut microbiota can play a critical role in this …