Duloxetine versus placebo in the treatment of major depressive disorder and associated painful physical symptoms: a replication study

PJ Gaynor, M Gopal, W Zheng… - … medical research and …, 2011 - Taylor & Francis
Objective: Painful physical symptoms are common in patients with major depressive
disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated …

A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms

PJ Gaynor, M Gopal, W Zheng… - … medical research and …, 2011 - Taylor & Francis
Objective: Painful physical symptoms are common in patients with major depressive
disorder (MDD) and may predict poorer treatment outcomes. Duloxetine has demonstrated …

[HTML][HTML] Efficacy of duloxetine on painful physical symptoms in major depressive disorder for patients with clinically significant painful physical symptoms at baseline: a …

SG Ball, D Desaiah, ME Spann… - The Primary Care …, 2011 - legacy.psychiatrist.com
Objective: To review efficacy of duloxetine for physical symptoms and depressive illness in
patients with at least mild to moderate major depressive disorder (MDD; DSM-IV) and …

Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder

SK Brannan, CH Mallinckrodt, EB Brown… - Journal of psychiatric …, 2005 - Elsevier
Background: While emotional symptoms such as depressed mood and loss of interest have
traditionally been considered to constitute the core symptoms of major depressive disorder …

[HTML][HTML] Efficacy and safety of duloxetine 60 mg once daily in major depressive disorder: a review with expert commentary

SG Ball, D Desaiah, Q Zhang, ME Thase… - Drugs in …, 2013 - ncbi.nlm.nih.gov
Objective: Major depressive disorder (MDD) is a significant public health concern and
challenges health care providers to intervene with appropriate treatment. This article …

Relationship between major depressive disorder and associated painful physical symptoms: analysis of data from two pooled placebo-controlled, randomized studies …

MJ Robinson, D Sheehan, PJ Gaynor… - International clinical …, 2013 - journals.lww.com
The aim of this study was to evaluate the relationship between painful physical symptoms
(PPS) and outcomes in major depressive disorder (MDD). Post-hoc analysis of two …

Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial

MJ Detke, Y Lu, DJ Goldstein, JR Hayes… - Journal of Clinical …, 2002 - psychiatrist.com
Background: Despite treatment advances, major depressive disorder (MDD) is still a
significant cause of morbidity and mortality. Current therapies frequently fall short of …

Effects of duloxetine on painful physical symptoms associated with depression

DJ Goldstein, Y Lu, MJ Detke, J Hudson, S Iyengar… - Psychosomatics, 2004 - Elsevier
Painful physical symptoms are common features of major depressive disorder and may be
the presenting complaints in primary care settings. The effect of the dual serotonin (5-HT) …

The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder

LM Arnold, AL Meyers, P Sunderajan… - Annals of Clinical …, 2008 - Taylor & Francis
Background. Patients with major depressive disorder (MDD) frequently report one or more
pain symptoms. To explore the relationship between improvement in pain symptoms and …

The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?

M Fava, CH Mallinckrodt, MJ Detke… - Journal of Clinical …, 2004 - psychiatrist.com
Background: Depression is a chronic disease consisting of emotional/psychological and
physical symptoms. Emotional symptoms have been shown to respond to currently available …