Percutaneous Cavopulmonary Assist: From Design to 96 Hour Survival in Lethal Cavopulmonary Failure Sheep

L Li, J Wang, G Zhao, S Topaz, D Morales… - ASAIO …, 2023 - journals.lww.com
We are developing a clinically practical percutaneous double lumen cannula (DLC)–based
cavopulmonary assist (CPA) system to support failing Fontan patients. In this study, our CPA …

PEDS17: Percutaneous Cavopulmonary Assist: From Design to 96 Hour Survival in Lethal Cavopulmonary Failure Sheep

L Li, G Zhao, S Topaz, C Ballard-Croft… - ASAIO …, 2022 - journals.lww.com
Purpose: We are developing a clinically practical percutaneous double lumen cannula
(DLC)-based cavopulmonary assist (CPA) system to support failing Fontan patients. In this …

Wang-Zwische double-lumen cannula leads to total cavopulmonary support in a failing Fontan sheep model

D Wang, M Plunkett, J Lynch, X Zhou… - The Annals of thoracic …, 2011 - Elsevier
Background We are developing a total cavopulmonary support system for failing Fontan
physiology using the percutaneous Wang-Zwische double-lumen cannula (DLC). Methods …

AvalonElite double lumen cannula for total cavopulmonary assist in failing Fontan sheep model with valved extracardiac conduit

C Zhou, D Wang, F Condemi, G Zhao, S Topaz… - Asaio …, 2019 - journals.lww.com
The AvalonElite double lumen cannula (DLC) provides total cavopulmonary assist (CPA) in
failing Fontan sheep, but recirculation limits reliability. To improve CPA performance, a two …

[HTML][HTML] A paired membrane umbrella double-lumen cannula ensures consistent cavopulmonary assistance in a Fontan sheep model

D Wang, G Gao, M Plunkett, G Zhao, S Topaz… - The Journal of thoracic …, 2014 - Elsevier
Objectives The Avalon Elite (Macquet, Rastatt, Germany) double-lumen cannula can provide
effective cavopulmonary assistance in a Fontan (total cavopulmonary connection) sheep …

[HTML][HTML] Percutaneous DLC-based total cavopulmonary assist achieves 96-hour survival in lethal cavopulmonary failure sheep

L Li, J Wang, G Zhao, S Topaz, D Morales… - Journal of the American …, 2021 - jacc.org
AUGUST 3, 2021: 537–4 4 538 overcome increased pulmonary vascular resistance,
resulting in multiorgan failure. Cavopulmonary assist (CPA) is required to drive total venous …

Feasibility of an animal model for cavopulmonary support with a double-outflow pump

M Granegger, A Escher, B Karner, M Kainz… - ASAIO …, 2023 - journals.lww.com
Both single-and double-outflow cavopulmonary assist devices (CPADs) were recently
proposed for the Fontan population, whereas single-outflow configurations were evaluated …

Recovery during mid-term mechanical support of Fontan circulation in sheep

S Tsuda, T Sasaki, K Maeda, RK Riemer… - Asaio …, 2009 - journals.lww.com
Total cavopulmonary connection (CPC) has a significant incidence of late failure due to
increased systemic venous pressure and low cardiac output. Mechanical support could …

Cavopulmonary assist: circulatory support for the univentricular Fontan circulation

MD Rodefeld, JH Boyd, CD Myers, BJ LaLone… - The Annals of thoracic …, 2003 - Elsevier
BACKGROUND: Following Fontan palliation, the univentricular circulation is notable for
coexisting systemic venous hypertension and pulmonary arterial hypotension. Assisted …

Target flow-pressure operating range for designing a failing Fontan cavopulmonary support device

M Farahmand, MN Kavarana… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Fontan operation as the current standard of care for the palliation of single ventricle defects
results in significant late complications. Using a mechanical circulatory device for the right …