Background: Fontan failure is emerging as an intractable problem for which current therapy
is only palliative. We report a chronic cavopulmonary assist device that has potential to …

Cavopulmonary assist (CPA) for failing Fontan patients remains a challenging issue in the
clinical setting. To evaluate the effectiveness of a partial CPA from the inferior vena cava …

The Fontan operation was described in 1971 by Fontan and Baudet 1 to palliate tricuspid
atresia. The physiology of this anatomic reconfiguration relies on postcapillary energy and a …

BACKGROUND: Cavopulmonary blood flow, rather than a systemic arterial source of
pulmonary blood flow, stabilizes Norwood physiology. We hypothesized that pump-assisted …

The Fontan operation is one of the greatest milestones in medicine and has saved the lives
of numerous children born with single-ventricle heart disease. 1 Fontan was among the first …

OBJECTIVES The 2 opposing inflows and 2 outflows in a total cavopulmonary connection
make mechanical circulatory support (MCS) extremely challenging. We have previously …

To provide hemodynamic support to patients with a failing single ventricle, we are
developing a percutaneously inserted, magnetically levitated axial flow blood pump …

The current methodology of Fontan palliation results in a one “pump” circulatory system with
passive flow to the lungs. Inherent hemodynamic differences exist between a biventricular …

We are developing a collapsible, percutaneously inserted, axial flow blood pump to support
the cavopulmonary circulation in infants with a failing single ventricle physiology. An initial …

OBJECTIVES Patients with a single ventricle survive thanks to the Fontan palliation.
Nevertheless, there is a growing number of Fontan patients with progressive heart failure. To …