Novel biomarkers for lupus nephritis in the “OMICS” Era

R Dias, UG Hasparyk, MP Lopes… - Current medicinal …, 2021 - ingentaconnect.com
Lupus nephritis (LN) is severe renal comorbidity associated with systemic lupus
erythematosus (SLE), a complex autoimmune disorder with high morbidity and mortality …

Metabolic profiling reveals new serum biomarkers of lupus nephritis

J Li, XW Xie, H Zhou, B Wang, MJ Zhang, FY Tang - Lupus, 2017 - journals.sagepub.com
Metabolomics has been applied to explore altered metabolite profiles in disease and identify
unique metabolic signatures specific to certain pathologies. The aim of the current study is to …

NMR-based serum metabolomics reveals reprogramming of lipid dysregulation following cyclophosphamide-based induction therapy in lupus nephritis

A Guleria, S Phatak, D Dubey, S Kumar… - Journal of proteome …, 2018 - ACS Publications
Lupus nephritis (LN) is a major cause of morbidity and mortality in lupus. Renal biopsy is the
gold standard for classification of nephritis, but because of its impracticality, new approaches …

Biomarker profiling for lupus nephritis

Y Li, X Fang, QZ Li - Genomics, proteomics & bioinformatics, 2013 - academic.oup.com
Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus
erythematosus (SLE), which is associated with significant morbidity and mortality of SLE …

Lupus nephritis biomarkers: a critical review

FK Alduraibi, GC Tsokos - International Journal of Molecular Sciences, 2024 - mdpi.com
Lupus nephritis (LN), a major complication in individuals diagnosed with systemic lupus
erythematosus, substantially increases morbidity and mortality. Despite marked …

Precision medicine in lupus nephritis: can biomarkers get us there?

DJ Caster, ML Merchant, JB Klein, DW Powell - Translational Research, 2018 - Elsevier
Patients with systemic lupus erythematosus frequently develop lupus nephritis (LN), a
condition that can lead to end-stage kidney disease. Multiple serum and urine biomarkers …

Metabolomics and biomarkers for lupus nephritis–a systematic review

FP Barone, SV Lourenço, LS Azevedo… - Surgical and …, 2023 - Springer
Background The development of personalized medicine using high-throughput methods,
such as metabolomics profiling, in discovering and validating biomarkers, may play a key …

Metabolic profiling reveals new serum signatures to discriminate lupus nephritis from systemic lupus erythematosus

Y Zhang, L Gan, J Tang, D Liu, G Chen… - Frontiers in …, 2022 - frontiersin.org
Background Lupus nephritis (LN) occurs in 50% of patients with systemic lupus
erythematosus (SLE), causing considerable morbidity and even mortality. Previous studies …

Urinary biomarkers for lupus nephritis: a systems biology approach

MH Omer, A Shafqat, O Ahmad, J Nadri… - Journal of Clinical …, 2024 - mdpi.com
Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disorder.
Kidney involvement, termed lupus nephritis (LN), is seen in 40–60% of patients with …

Discovery and qualification of candidate urinary biomarkers of disease activity in lupus nephritis

VG Anania, K Yu, F Pingitore, Q Li… - Journal of proteome …, 2018 - ACS Publications
Lupus nephritis (LN) is a severe clinical manifestation of systemic lupus erythematosus
(SLE) associated with significant morbidity and mortality. Assessment of severity and activity …