Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

The power of imaging to understand extracellular vesicle biology in vivo

FJ Verweij, L Balaj, CM Boulanger, DRF Carter… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

[HTML][HTML] Toward characterizing extracellular vesicles at a single-particle level

C Chiang, C Chen - Journal of biomedical science, 2019 - Springer
Extracellular vesicles (EVs) are cell-derived membrane-bound vesicles that serve a means
of cell-cell communication. Studying EVs at a single-particle level is important because EVs …

Emerging technologies for profiling extracellular vesicle heterogeneity

G Huang, G Lin, Y Zhu, W Duan, D Jin - Lab on a Chip, 2020 - pubs.rsc.org
Extracellular vesicles (EVs) are membrane-bound vesicles secreted by most cell types and
exist in virtually all bodily fluids. They carry on a wealth of proteomic and genetic information …

[HTML][HTML] Extracellular vesicle quantification and characterization: common methods and emerging approaches

TA Hartjes, S Mytnyk, GW Jenster, V van Steijn… - Bioengineering, 2019 - mdpi.com
Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …

[HTML][HTML] Advances in the analysis of single extracellular vesicles: A critical review

SH Hilton, IM White - Sensors and actuators reports, 2021 - Elsevier
There is an ever-growing need for new cancer diagnostic approaches that provide earlier
diagnosis as well as richer diagnostic, prognostic, and resistance information. Extracellular …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Future of digital assays to resolve clinical heterogeneity of single extracellular vesicles

RTT Morales, J Ko - ACS nano, 2022 - ACS Publications
Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

[HTML][HTML] Multiplexed profiling of extracellular vesicles for biomarker development

C Jiang, Y Fu, G Liu, B Shu, J Davis, GK Tofaris - Nano-micro letters, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …