[HTML][HTML] Rigor and standardization of extracellular vesicle research: Paving the road towards robustness

R Nieuwland, JM Falcón‐Pérez, C Théry… - Journal of Extracellular …, 2020 - ncbi.nlm.nih.gov
Accompanying the growing awareness that extracellular vesicles (EVs) are useful for
diagnostics and therapeutics is the realization that EV applications must be established with …

[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Extracellular vesicles: the growth as diagnostics and therapeutics; a survey

S Roy, FH Hochberg, PS Jones - Journal of extracellular vesicles, 2018 - Taylor & Francis
This article aims to document the growth in extracellular vesicle (EV) research. Here, we
report the growth in EV-related studies, patents, and grants as well as emerging companies …

A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity

X Zhang, EGF Borg, AM Liaci, HR Vos… - Journal of extracellular …, 2020 - Taylor & Francis
Extracellular vesicles (EV) are membrane encapsulated nanoparticles that can function in
intercellular communication, and their presence in biofluids can be indicative for (patho) …

[HTML][HTML] Extracellular vesicle isolation: present and future

I Furi, F Momen-Heravi, G Szabo - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
In recent years, extracellular vesicle (EV)-based biomarker discovery has received
significant interest amongst scientist studying diverse disease conditions. Extracellular …

[HTML][HTML] Imaging extracellular vesicles: current and emerging methods

STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …

[HTML][HTML] Impact of isolation methods on the biophysical heterogeneity of single extracellular vesicles

S Sharma, M LeClaire, J Wohlschlegel… - Scientific Reports, 2020 - nature.com
Extracellular vesicles (EVs) have raised high expectations as a novel class of diagnostics
and therapeutics. However, variabilities in EV isolation methods and the unresolved …

[HTML][HTML] Comparison of extracellular vesicle isolation and storage methods using high-sensitivity flow cytometry

S Deville, P Berckmans, R Van Hoof, I Lambrichts… - PLoS …, 2021 - journals.plos.org
Extracellular vesicles (EVs) are of interest for a wide variety of biomedical applications. A
major limitation for the clinical use of EVs is the lack of standardized methods for the fast and …

Proteomic insights into extracellular vesicle biology–defining exosomes and shed microvesicles

DW Greening, R Xu, SK Gopal, A Rai… - Expert review of …, 2017 - Taylor & Francis
ABSTRACT Introduction: Extracellular vesicles (EVs) are critical mediators of intercellular
communication, capable of regulating the transcriptional landscape of target cells through …

[HTML][HTML] Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry

S Mastoridis, GM Bertolino, G Whitehouse… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs) are responsible for a multitude of physiological functions,
including immunomodulation. A heterogenous mixture of small EV (sEV) subsets, including …