Single-vesicle assays using liposomes and cell-derived vesicles: from modeling complex membrane processes to synthetic biology and biomedical applications
The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …
contradistinction to the extracellular environment. The plasma membrane not only serves as …
Advancement and obstacles in microfluidics-based isolation of extracellular vesicles
M Havers, A Broman, A Lenshof, T Laurell - Analytical and Bioanalytical …, 2023 - Springer
There is a great need for techniques which enable reproducible separation of extracellular
vesicles (EVs) from biofluids with high recovery, purity and throughput. The development of …
vesicles (EVs) from biofluids with high recovery, purity and throughput. The development of …
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
J Kowal, G Arras, M Colombo… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) have become the focus of rising interest because of their
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …
Ultrasensitive single extracellular vesicle detection using high throughput droplet digital enzyme-linked immunosorbent assay
Extracellular vesicles (EVs) have attracted enormous attention for their diagnostic and
therapeutic potential. However, it has proven challenging to achieve the sensitivity to detect …
therapeutic potential. However, it has proven challenging to achieve the sensitivity to detect …
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion …
JA Martínez‐Greene… - Journal of …, 2021 - Wiley Online Library
The molecular characterization of extracellular vesicles (EVs) has revealed a great
heterogeneity in their composition at a cellular and tissue level. Current isolation methods …
heterogeneity in their composition at a cellular and tissue level. Current isolation methods …
Diurnal variations of circulating extracellular vesicles measured by nano flow cytometry
KM Danielson, J Estanislau, J Tigges, V Toxavidis… - PloS one, 2016 - journals.plos.org
The identification of extracellular vesicles (EVs) as intercellular conveyors of biological
information has recently emerged as a novel paradigm in signaling, leading to the …
information has recently emerged as a novel paradigm in signaling, leading to the …
Extracellular vesicles: translational challenges and opportunities
H Clemmens, DW Lambert - Biochemical Society Transactions, 2018 - portlandpress.com
Extracellular vesicles (EVs) are a heterogeneous group of small lipid-enclosed structures
with myriad roles in physiology and disease. The recent surge of interest in EVs has led to …
with myriad roles in physiology and disease. The recent surge of interest in EVs has led to …
Advanced microfluidic technologies for isolating extracellular vesicles
Extracellular vesicles (EVs) are lipid membrane-enclosed, cell-secreted nanovesicles that
have attracted significant attentions in recent years in view of their potential as non-invasive …
have attracted significant attentions in recent years in view of their potential as non-invasive …
Framework for rapid comparison of extracellular vesicle isolation methods
D Ter-Ovanesyan, M Norman, R Lazarovits, W Trieu… - Elife, 2021 - elifesciences.org
Extracellular vesicles (EVs) are released by all cells into biofluids and hold great promise as
reservoirs of disease biomarkers. One of the main challenges in studying EVs is a lack of …
reservoirs of disease biomarkers. One of the main challenges in studying EVs is a lack of …
Integrated microfluidic device for accurate extracellular vesicle quantification and protein markers analysis directly from human whole blood
S Zhou, T Hu, F Zhang, D Tang, D Li, J Cao… - Analytical …, 2019 - ACS Publications
Extracellular vesicles (EVs) have the potential to be utilized as disease-specific biomarkers.
Although strategies for on-chip isolation and detection of EVs have recently been …
Although strategies for on-chip isolation and detection of EVs have recently been …