Reactive oxygen and nitrogen species in the renal ischemia/reperfusion injury

F Rodriguez, B Bonacasa, FJ Fenoy… - Current …, 2013 - ingentaconnect.com
Renal ischemia is the most common cause of acute kidney injury (AKI) still associated with
high mortality rates of about 50% in the intensive care unit. Postischemic AKI is …

The pathogenesis of acute kidney injury and the toxic triangle of oxygen, reactive oxygen species and nitric oxide

U Aksu, C Demirci, C Ince - Controversies in Acute Kidney Injury, 2011 - karger.com
Despite the identification of several of the cellular mechanisms thought to underlie the
development of acute kidney injury (AKI), the pathophysiology of AKI is still poorly …

Ischemia-reperfusion: From cell biology to acute kidney injury

N Chatauret, L Badet, B Barrou, T Hauet - Progrès en urologie, 2014 - Elsevier
Ischemia reperfusion injury occurs in the kidney when blood supply is interrupted in clinical
settings such as kidney transplantation or nephron sparing surgery for renal tumors. These …

Novel pharmacological approaches to the treatment of renal ischemia-reperfusion injury: a comprehensive review

PK Chatterjee - Naunyn-Schmiedeberg's archives of pharmacology, 2007 - Springer
Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Renal hypoxia and dysoxia after reperfusion of the ischemic kidney

M Legrand, EG Mik, T Johannes, D Payen, C Ince - Molecular medicine, 2008 - Springer
Ischemia is the most common cause of acute renal failure. Ischemic-induced renal tissue
hypoxia is thought to be a major component in the development of acute renal failure in …

The role of the microcirculation in acute kidney injury

M Le Dorze, M Legrand, D Payen… - Current opinion in critical …, 2009 - journals.lww.com
Knowledge of the pathophysiological mechanisms of acute kidney injury emphasizes the
importance of the role of the microcirculation in its development. Preventive and therapeutic …

[HTML][HTML] Renal ischemia/reperfusion injury; from pathophysiology to treatment

M Malek, M Nematbakhsh - Journal of renal injury prevention, 2015 - ncbi.nlm.nih.gov
Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

The central role of renal microcirculatory dysfunction in the pathogenesis of acute kidney injury

C Ince - Nephron Clinical Practice, 2014 - karger.com
Acute kidney injury (AKI) is a rapidly developing condition often associated with critical
illness, with a high degree of morbidity and mortality, whose pathophysiology is ill …

Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease

P Singh, SE Ricksten, G Bragadottir… - Clinical and …, 2013 - Wiley Online Library
Acute kidney injury (AKI) is a major burden on health systems and may arise from multiple
initiating insults, including ischaemia‐reperfusion injury, cardiovascular surgery …

Reactive oxygen species and acute renal failure

KA Nath, SM Norby - The American journal of medicine, 2000 - Elsevier
Acute renal failure is commonly due to acute tubular necrosis (ATN), the latter representing
an acute, usually reversible loss of renal function incurred from ischemic or nephrotoxic …