MicroRNAs as serum biomarkers in Becker muscular dystrophy

D Gagliardi, M Rizzuti, R Brusa… - Journal of Cellular …, 2022 - Wiley Online Library
Becker muscular dystrophy (BMD) is an X‐linked neuromuscular disorder due to mutation in
the DMD gene, encoding dystrophin. Despite a wide clinical variability, BMD is …

Longitudinal study of three microRNAs in Duchenne muscular dystrophy and Becker muscular dystrophy

S Trifunov, D Natera-de Benito… - Frontiers in …, 2020 - frontiersin.org
Our objective was to investigate the potential of three microRNAs, miR-181a-5p, miR-30c-
5p, and miR-206 as prognostic biomarkers for long-term follow up of Duchenne muscular …

Circulating muscle-specific miRNAs in Duchenne muscular dystrophy patients

X Li, Y Li, L Zhao, D Zhang, X Yao, H Zhang… - … Therapy-Nucleic Acids, 2014 - cell.com
Noninvasive biomarkers with diagnostic value and prognostic applications have long been
desired to replace muscle biopsy for Duchenne muscular dystrophy (DMD) patients …

MiRNAs, myostatin, and muscle MRI imaging as biomarkers of clinical features in becker muscular dystrophy

R Marozzo, V Pegoraro, C Angelini - Diagnostics, 2020 - mdpi.com
Becker muscular dystrophy (BMD) is an X-linked recessive disorder caused by dystrophin
gene mutations. The phenotype and evolution of this muscle disorder are extremely clinical …

Noncoding RNAs in Duchenne and Becker muscular dystrophies: role in pathogenesis and future prognostic and therapeutic perspectives

R Brusa, F Magri, N Bresolin, GP Comi… - Cellular and Molecular Life …, 2020 - Springer
Noncoding RNAs (ncRNAs), such as miRNAs and long noncoding RNAs, are key regulators
of gene expression at the post-transcriptional level and represent promising therapeutic …

[HTML][HTML] Serum MyomiRs as biomarkers for female carriers of Duchenne/Becker muscular dystrophy

J Zhang, Q Meng, J Zhong, M Zhang, X Qin, X Ni… - Frontiers in …, 2020 - frontiersin.org
Background: Duchenne/Becker muscular dystrophy (DMD/BMD) is an X-linked recessive
lethal neuromuscular disease. MicroRNAs expressed in striated muscle, myomiRs, have …

[PDF][PDF] TNF-α-induced microRNAs control dystrophin expression in Becker muscular dystrophy

AA Fiorillo, CR Heier, JS Novak, CB Tully, KJ Brown… - Cell reports, 2015 - cell.com
The amount and distribution of dystrophin protein in myofibers and muscle is highly variable
in Becker muscular dystrophy and in exon-skipping trials for Duchenne muscular dystrophy …

MicroRNAs in dystrophinopathy

A Lee, J Moon, J Yu, C Kho - International Journal of Molecular Sciences, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), which
represent the range of dystrophinopathies, account for nearly 80% of muscle dystrophy …

Circulating miRNAs are generic and versatile therapeutic monitoring biomarkers in muscular dystrophies

D Israeli, J Poupiot, F Amor, K Charton, W Lostal… - Scientific reports, 2016 - nature.com
The development of medical approaches requires preclinical and clinical trials for
assessment of therapeutic efficacy. Such evaluation entails the use of biomarkers, which …

Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy

H Mizuno, A Nakamura, Y Aoki, N Ito, S Kishi… - PloS one, 2011 - journals.plos.org
Duchenne muscular dystrophy (DMD) is a lethal X-linked disorder caused by mutations in
the dystrophin gene, which encodes a cytoskeletal protein, dystrophin. Creatine kinase (CK) …