[HTML][HTML] The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

KF Bol, G Schreibelt, K Rabold, SK Wculek… - … for immunotherapy of …, 2019 - Springer
Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …

[HTML][HTML] Dendritic cells in cancer vaccines

P Brossart, S Wirths, W Brugger, L Kanz - Experimental hematology, 2001 - Elsevier
Dendritic cells (DC) are recognized as the most potent antigen-presenting cells with the
ability to stimulate naive resting T cells and to initiate primary immune responses …

Dendritic cell–based immunotherapy: state of the art and beyond

KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …

Dendritic cells in cancer immunotherapy: vaccines and combination immunotherapies

P Kalinski, R Muthuswamy, J Urban - Expert review of vaccines, 2013 - Taylor & Francis
Dendritic cells (DCs) are specialized immunostimulatory cells involved in the induction and
regulation of immune responses. The feasibility of large-scale ex vivo generation of DCs …

Dendritic-cell-based therapeutic vaccination against cancer

FO Nestle, A Farkas, C Conrad - Current opinion in immunology, 2005 - Elsevier
Early clinical trials, in which over 1000 cancer patients received dendritic cell (DC) vaccines,
tested different vaccine preparations, but they did not always induce sufficient acquired …

[HTML][HTML] Dendritic cells in anticancer vaccination: rationale for ex vivo loading or in vivo targeting

AV Baldin, LV Savvateeva, AV Bazhin, AA Zamyatnin Jr - Cancers, 2020 - mdpi.com
Dendritic cells (DCs) have shown great potential as a component or target in the landscape
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …

Dendritic cells: a critical player in cancer therapy?

AK Palucka, H Ueno, J Fay… - Journal of …, 2008 - journals.lww.com
Cancer immunotherapy seeks to mobilize a patient's immune system for therapeutic benefit.
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …

Dendritic cell therapy in cancer treatment; the state-of-the-art

M Sadeghzadeh, S Bornehdeli… - Life sciences, 2020 - Elsevier
Dendritic cells (DCs) are considered as professional antigen presenting cells (APCs),
containing a variety of subsets, that can be resident in organs or migrating among the …

[HTML][HTML] Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets

F Wimmers, G Schreibelt, AE Sköld, CG Figdor… - Frontiers in …, 2014 - frontiersin.org
Dendritic cell (DC)-based immunotherapy employs the patients' immune system to fight
neoplastic lesions spread over the entire body. This makes it an important therapy option for …

The use of dendritic cells in cancer immunotherapy

A Nencioni, F Grünebach, SM Schmidt… - Critical reviews in …, 2008 - Elsevier
Cancer immunotherapy aims at eliciting an immune response directed against tumor
antigens to help fight off residual tumor cells and thereby improve survival and quality of life …